neurolathyrism


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Related to neurolathyrism: aflatoxin, ergotism, Epidemic dropsy

neurolathyrism

[¦nu̇r·ō′lath·ə‚riz·əm]
(medicine)
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Its seeds contain a neuron-toxic substance called ODAP [[beta]-N-Oxalyl-L-[alpha], [beta]-diaminopropanoic acid] which causes a disease known as neurolathyrism that results in paralysis of the lower body on the people who consume it continuously.
Onset in late childhood or early adolescence is seen in certain epilepsy syndromes (3,5), autoimmune diseases such as juvenile idiopathic arthritis (23), Sydenham chorea and other complications of group A streptococcal infections (24), and some nutritional toxicities such as konzo (25) and neurolathyrism (26).
It has been known to cause neurolathyrism which is characterized by the paralysis of the legs and has many qualities that are similar to Parkinsons disease.