neuromuscular junction


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neuromuscular junction

[¦nu̇r·ō′məs·kyə·lər ′jəŋk·shən]
(anatomy)
References in periodicals archive ?
Sellin LC, Kauffman JA, DasGupta BR (1983) Comparison of effects of botulinum neurotoxin types A and E at the rat neuromuscular junction.
A neuromuscular junction is comprised of three components--the presynaptic membrane, the synaptic cleft, and the postsynaptic membrane.
Neurotune has developed a novel class of compounds to maintain neuromuscular junction strength and stability.
Finally, the introductory chapter and final chapter on the formation and plasticity of the neuromuscular junction greatly overlap and could have been co-authored to avoid repetition.
The receptors are unique and localized to the neuromuscular junction.
Among the causes they listed low pseudocholinesterase levels, general debility, factors related to general anaesthesia and pathological changes to the neuromuscular junction.
She is best known for identifying new targets for autoantibodies in neuromuscular junction disorders and in non-paraneoplastic brain diseases, and for establishing diagnostic assays for these conditions.
The product is administered in small therapeutic doses by injection directly into the affected area, and works by blocking the release of acetylcholine (a neurotransmitter that signals the muscles to contract) at the neuromuscular junction.
The active ingredient in Dysport([R]) is a botulinum toxin type A, which acts at the level of the neuromuscular junction in the targeted muscle.
Ester has demonstrated the utility of its genome-based approach to AChE neuromodulation using its antisense drug candidate EN101 in experimental myasthenia gravis, a progressive muscle weakness due to auto-antibodies blocking of the acetylcholine receptors in the neuromuscular junction, which is currently undergoing human trials.
Neuromuscular Junction Testing: Repetitive Nerve Stimulation and Single Fiber EMG
He pioneered the use of cultured neurons and muscle cells to characterize the biochemical, cellular, and electrophysiological mechanisms underlying development and function of the neuromuscular junction.

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