enolase

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enolase

[′ē·nə‚lās]
(biochemistry)
An enzyme that catalyzes the reversible dehydration of phosphoglyceric acid to phosphopyruvic acid.
References in periodicals archive ?
Yandi, "The prognostic value of neuron-specific enolase in head trauma patients," The Journal of Emergency Medicine, vol.
The tumor stains positively for (b) neuron-specific enolase, (c) vimentin, (d) synaptophysin, and (e) S-100 protein.
[AFP: Alfa fetoprotein; [beta]-hCG: Beta human chorionic gonadotropin; CA: Carbohydrate antigen; CEA: Carcinoembryonic antigen; HCC: Hepatocellular carcinoma; LASA-P: Lipid-associated sialic acid P; MEN: Multiple endocrine neoplasia; NSE: Neuron-specific enolase; PSA: Prostate-specific antigen; SCC-A: Squamous cell carcinoma antigen.]
However, neuron-specific enolase (NSE) was significantly higher (289.46 ng/mL, normal level <16.3 ng/mL).
Immunohistochemical studies showed positive immunoreactivity of neoplastic cells to cytokeratin and chromogranin [Figure 4a and b], and negative reactivity with AFP, CEA, vimentin, leukocyte common antigen (LCA), CD20 antigen, and neuron-specific enolase (NSE).
On immunohistochemical staining, the tumor was strongly positive for SI00, neuron-specific enolase, and vimentin and was weakly positive for glial fibrillary acidic protein stain (Table 1).
It measures both neuron-specific enolase (NSE) and Pro-gastrin-releasing peptide (ProGRP), which enhances diagnostic accuracy.
To exclude the different cells origin of this tumor, other immunohistochemical staining were done: pancytokeratin (-), chromogranin A (-), SMA (-), CD117 (-) CD45 (-) Neuron-specific enolase (-) (Fig 1a.
Paragangliomas will show positivity for neuron-specific enolase, chromogranin A and synaptophysin as well as S100 protein positivity for sustentacular cells and are negative for thyroglobulin and calcitonin.
Specifically, 6 weeks ago, MRI of the brain demonstrated restricted diffusion in the left occipital lobe, and cerebrospinal fluid (CSF) neuron-specific enolase was moderately elevated at 34 ng/mL.

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