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Any disease affecting neurons.



a functional weakness of the nervous system accompanied by a decrease in the absolute threshold (also called the stimulus, or sensitivity, threshold); the condition is frequently congenital.

Neuropathy arises as a disturbance in the function of the autonomic nervous system owing to deleterious influences on the fetus as a whole (for example, infection in the pregnant mother, trauma, or poisoning) or on the individual embryonic cells (as occurs when the parents suffer from alcoholism). Family circumstances, upbringing, and illnesses suffered by the infant play a role in the pathogenesis of neuropathy. The symptoms usually emerge in childhood or adolescence. When neuropathy occurs in early childhood, disturbances of sleep and appetite are most characteristic; the infant has difficulty in falling asleep, awakes easily, suckles poorly, and frequently spits up. Later, vomiting occurs, and either diarrhea or constipation develop.

From the preschool years on, increased general excitability and the rapid onset of fatigue and exhaustion are observed, in addition to continued disturbances of sleep and appetite. Children who suffer from neuropathy blush easily in response to irritation. Motor hyperactivity, nervous tics, and stammering are frequent. In adolescence, autonomic-vascular instability becomes more acute, as evidenced by frequently occurring nervous palpitation, abrupt shifts in blood pressure, headaches, dizzy spells, and fainting spells. The prognosis is favorable, with the neuropathic symptoms usually disappearing with age.


Simson, T. Nevropatii, psikhopatii i reaktivnye sostoianiia mladencheskogo vozrasta. Moscow-Leningrad, 1929.
Sukhareva, G. E. Klinicheskie lektsii po psikhiatrii detskogo vozrasta, vol. 2. Moscow, 1959.


References in periodicals archive ?
About CMT Charcot-Marie-Tooth (CMT) disease, also known as Hereditary Motor and Sensory Neuropathy (HMSN) or Peroneal Muscular Atrophy (PMA), encompasses a heterogeneous group of inherited, progressive, chronic sensory and motor peripheral neuropathies.
HNF and HHF last year launched the Global Registry for Inherited Neuropathies (GRIN) to collect clinical and genetic information on patients diagnosed with the various forms of inherited neuropathies in order to advance therapy development for these debilitating disorders.
The second most commonly affected peripheral nerve in nontraumatic focal neuropathies was the ulnar nerve.
Long thoracic nerve, suprascapular nerve, sciatic and femoral nerve entrapment neuropathies, tarsal tunnel syndrome, Morton's neuroma, Meralgia paresthetica, and peroneal nerve neuropathy were the least common focal neuropathies (less than 1%) (Table 4).
The Company currently markets products for the detection, diagnosis, and monitoring of diabetic neuropathies such as diabetic peripheral neuropathy and median neuropathy (carpal tunnel syndrome).
Vinik was co-author of the ADA's position statement on diabetic neuropathies.
His research includes studies of the pathophysiology, prevention, and treatment of diabetic neuropathies.
This report specifically focuses on key CNS diseases, such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, Huntington's disease, and neuropathies.
Nasdaq: NURO), a medical device company focused on the development and sale of proprietary products used to diagnose neuropathies and neurovascular disease, noted that in the past two months three new peer-reviewed journal articles have been published covering various aspects of the NC-stat System, providing further validation for the utility and accuracy of conventional nerve conduction studies performed with the NC-stat System.
NASDAQ: NURO), a medical device company focused on the development and sale of proprietary products used to diagnose neuropathies, announced today that it is scheduled to present at the Ninth Annual Growth Conference of Needham & Company, LLC at The New York Palace Hotel in New York City at 3:30pm (EST) on Thursday, January 11, 2007.
Nasdaq: NURO), a medical device company focused on the development and sale of proprietary products used to diagnose neuropathies, including diabetic peripheral neuropathy, announced today that it has signed an exclusive licensing agreement with EyeTel Imaging, Inc.