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Any disease affecting neurons.



a functional weakness of the nervous system accompanied by a decrease in the absolute threshold (also called the stimulus, or sensitivity, threshold); the condition is frequently congenital.

Neuropathy arises as a disturbance in the function of the autonomic nervous system owing to deleterious influences on the fetus as a whole (for example, infection in the pregnant mother, trauma, or poisoning) or on the individual embryonic cells (as occurs when the parents suffer from alcoholism). Family circumstances, upbringing, and illnesses suffered by the infant play a role in the pathogenesis of neuropathy. The symptoms usually emerge in childhood or adolescence. When neuropathy occurs in early childhood, disturbances of sleep and appetite are most characteristic; the infant has difficulty in falling asleep, awakes easily, suckles poorly, and frequently spits up. Later, vomiting occurs, and either diarrhea or constipation develop.

From the preschool years on, increased general excitability and the rapid onset of fatigue and exhaustion are observed, in addition to continued disturbances of sleep and appetite. Children who suffer from neuropathy blush easily in response to irritation. Motor hyperactivity, nervous tics, and stammering are frequent. In adolescence, autonomic-vascular instability becomes more acute, as evidenced by frequently occurring nervous palpitation, abrupt shifts in blood pressure, headaches, dizzy spells, and fainting spells. The prognosis is favorable, with the neuropathic symptoms usually disappearing with age.


Simson, T. Nevropatii, psikhopatii i reaktivnye sostoianiia mladencheskogo vozrasta. Moscow-Leningrad, 1929.
Sukhareva, G. E. Klinicheskie lektsii po psikhiatrii detskogo vozrasta, vol. 2. Moscow, 1959.


References in periodicals archive ?
The asymmetric neuropathies can also be divided into those with acute onset and those with gradual onset.
Diabetic neuropathies tend to develop slowly over the years, either progressing undetected or presenting with nonspecific symptoms that mimic those seen in other diseases, requiring diagnosis by exclusion.
Disease mechanisms in hereditary sensory and autonomic neuropathies.
3) In electrodiagnostic terms, these neuropathies are almost always primarily axonal rather than demyelinating, usually involving both large and small nerve fibers.
Belen said she could not draw a conclusion that Zyvox was responsible for the neuropathies reported, since the adverse event report database is just a passive collector of information.
Diabetic neuropathies can be classified as peripheral, autonomic, proximal, and focal.
The relationship between the host's nutritional status and virus evolution could be key in understanding the cause of epidemic neuropathy, the Tanzanian epidemic of optic neuropathy, and other tropical epidemic neuropathies.
The main advantage of F-wave methodology has been in the detection of peripheral neuropathies in which F-waves may show clinically significant and measurable changes even before Conventional nerve conduction studies are informative.
Few study subjects also had mono neuropathies and pure sensory neuropathies.
Gozani intends to provide an update on the Company's business activities and on its diabetes products including NC-stat([R]) DPNCheck([TM]), a diagnostic test for systemic neuropathies such as diabetic peripheral neuropathy (DPN), and the SENSUS[TM] pain management device for relief of chronic intractable pain.