neuropore

Also found in: Dictionary, Medical, Wikipedia.

Related to neuropore: anterior neuropore

neuropore

[′nu̇r·ō‚pȯr]

(embryology)

A terminal aperture of the neural tube before complete closure at the 20-25 somite stage.

Mentioned in ?

Nervous system disorders

References in periodicals archive ?

In addition, Neuropore reports the successful completion of the initial, single dose, safety and the food effect studies of NPT520-34 in healthy volunteers.

Neuropore Receives Orphan Drug Designation for NPT520-34 for the Treatment of Amyotrophic Lateral Sclerosis

Errol De Souza, President and CEO of Neuropore, stated, 'We are very pleased with receiving this orphan drug designation from the FDA's Office of Orphan Product Development for NPT520-34 for the treatment of ALS, a devastating disease with a very high unmet medical need.

Neuropore Receives Orphan Drug Designation for NPT520-34 for the Treatment of Amyotrophic Lateral Sclerosis August 14, 2019

In (ct-/ct-) mice, both the posterior endoderm and the notochord grow slowly, and the unbalanced growth between ventral and dorsal tissue causes an excessive curvature of the caudal region, which in turn induces a delay in the closure of the posterior neuropore, resulting in the curly tail phenotype, or in more severe closure defect, represented by spina bifida.

Myoinositol: The Bridge (PONTI) to Reach a Healthy Pregnancy

Under the transaction, UCB will receive the world-wide exclusive license to develop and commercialise Neuropore's new small molecule NPT200-11in all indications.

Neuropore Therapies signs contract with UCB

A short distance posterior to the cross-sectional level in Figure 4G, the stomochord and perihaemal coeloms disappear, and the collar cord emerges at the posterior neuropore to continue as the dorsal nerve cord of the trunk.

An externally brooding acorn worm hemichordata, enteropneusta, torquaratoridae from the Russian Arctic

Moreover, 7-OH-AAF was the principle metabolite of AF and it was responsible for causing abnormal incomplete closure of the posterior neuropore in rat embryos and producing a morphologically distinguishable defect (Stark et al., 1989).

Oral administration of paclitaxel affects the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats

Errol De Souza, President and CEO of Neuropore, stated, 'We are very excited to establish this collaboration with BenevolentAI.

Neuropore Therapies and BenevolentAI Enter Strategic Collaboration to Discover Novel Therapeutics through the Application of Artificial Intelligence

Neuropore will receive a USD 5m award as a result of achieving this milestone.

UCB Initiates Phase 1b US-Based Multicenter Clinical Trial in Parkinson's Disease Patients with UCB0599, a Compound Arising from the Neuropore-UCB Collaboration

Spina bifida with rachischisis occurs when the posterior neuropore of the neural tube fails to close during week 4 of development.

Meningomyelocele: case report with its embryological basis

By E5, the neural rod is almost entirely detached from the dorsal epithelial layer, except at the most posterior level of neuropore. At about E6, the rod cavitates to form a columnar neural tube, and the head extends.

Insights from a sea lamprey into the evolution of neural crest gene regulatory network

M2 PHARMA-January 25, 2017-Errol De Souza Named President, CEO at Neuropore Therapies

Errol De Souza Named President, CEO at Neuropore Therapies

The supposed actin dependency of anterior but not posterior neuropore closure in mouse embryos (Ybot-Gonzalez and Copp 1999) could thus explain why exencephaly is the dominant NTD observed in VPA-exposed mice (Nau et al.