neuropore


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Related to neuropore: anterior neuropore

neuropore

[′nu̇r·ō‚pȯr]
(embryology)
A terminal aperture of the neural tube before complete closure at the 20-25 somite stage.
References in periodicals archive ?
has been appointed president and chief executive officer of US-based biopharmaceutical company Neuropore Therapies, Inc.
The transaction will see an initial upfront payment of USD20m made to Neuropore, which is also entitled to potential development, regulatory and sales-based milestones payments, of up to a potential total of USD460m in addition to royalties on net sales.
A short distance posterior to the cross-sectional level in Figure 4G, the stomochord and perihaemal coeloms disappear, and the collar cord emerges at the posterior neuropore to continue as the dorsal nerve cord of the trunk.
Moreover, 7-OH-AAF was the principle metabolite of AF and it was responsible for causing abnormal incomplete closure of the posterior neuropore in rat embryos and producing a morphologically distinguishable defect (Stark et al.
Stage 11: Closure of the Rostral Neuropore and the Beginning of Secondary Neurulation.
Spina bifida with rachischisis occurs when the posterior neuropore of the neural tube fails to close during week 4 of development.
By E5, the neural rod is almost entirely detached from the dorsal epithelial layer, except at the most posterior level of neuropore.
The supposed actin dependency of anterior but not posterior neuropore closure in mouse embryos (Ybot-Gonzalez and Copp 1999) could thus explain why exencephaly is the dominant NTD observed in VPA-exposed mice (Nau et al.
Ventrally the coelom ends in a blind sac; dorsally it extends extremely posteriorly into the stalk and opens to the outside through a single proboscis pore just left of the dorsal midline of the proboscis stalk and almost into the anterior neuropore.