Autologous platelet-rich plasma has been demonstrated to be effective in corneal neurotrophic ulcer treatment.
The group of scientists treated more than 45 eyes with moderate and severe neurotrophic ulcers with nerve growth factor eye drops observing healing in almost 100% of the cases .
Muraine, "Topical treatment with a new matrix therapy agent (RGTA) for the treatment of corneal neurotrophic ulcers," Investigative Opthalmology and Visual Science, vol.
Internal amputation is also a good option for both treatment and prophylaxis of neurotrophic ulcers
due to claw foot deformity.
Marjolin's ulcer, first described by the late French surgeon Jean-Nicolas Marjolin in 1828, is the malignant transformation of long-standing burns, fissures, and ulcers, including leprous neurotrophic ulcers
, and other chronically inflamed tissue processes .
Ocular diseases requiring lid fusion included, infective corneal ulcer/abscess in 21 (65.6%) cases, shield ulcer in vernal keratoconjunctivitis in 3 (9.4 %)cases, facial palsy in 2 (6.2%) cases, alkali burns in 2 (6.2 %)case, neurotrophic ulcer
in 2 (6.2 %)cases, Mooren ulcer in 1 (3.1%) case, Grave's disease in 1 (3.1%) case (Table).
et al (11) reviewed 47 cases of neurotrophic ulcers
of which 6 were due to syringomyelia and 4 had old spinal cord injury.