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A large granular leukocyte with a highly variable nucleus, consisting of three to five lobes, and cytoplasmic granules which stain with neutral dyes and eosin.



(also called polymorphonuclear neutrophil leukocyte, microphage), a type of white blood cell, or leukocyte, occurring in vertebrates and man. The diameter of a neutrophil ranges from 9 to 12 μ. The cytoplasm of these cells contains granules that attract both basic and acidic dyes, and this is why these leukocytes are called neutrophils.

A neutrophil is classified according to its degree of maturity: a metamyelocyte is a young neutrophil with an unsegmented nucleus, a rod neutrophil has a nucleus in the shape of a curved rod, and segmented, or filamented, neutrophils have segmented nuclei. Neutrophils are phagocytes that are capable of ingesting small foreign particles, including microbes. By elaborating hydrolytic enzymes, neutrophils can lyse dead tissue. Neutrophilia is an abnormal increase in the concentration of neutrophils in the blood. (SeeLEUKOCYTOSIS.)

References in periodicals archive ?
Cellular defence includes proliferation and activation of lymphocytes as well as induction of phagocytosis of macrophages and neutrophile granulocytes.
The neutrophile PMN could infiltrate the muscle tissue damaged by high-density exercise.
Third isoform inducible (iNOS) is highly expressed in macrophages, neutrophiles, endothelial and smooth muscle cells upon different stimuli.
red blood cells (RBC), w hite blood cells (WBC) and principal derivative subpopulations such as monocytes (MO), neutrophiles (NE) and lymphocytes (LY)).
Peripheral smear findings were as follows: neutrophiles 50%, lymphocytes 44%, monocytes 4% and bands 2%.
3], 65% neutrophiles, 35% lymphocytes and 5% eosynophiles; platelets 251,000 [mm.
The level and nature of conjunctiva inflammation (lymphoplasmocytes, neutrophiles, granulomatose, neutrophiles-lymphocytes and neutrophilesplasmocytes); duct alterations (inflammation, dilation, scaling metaplasia); and glandular alterations (inflammation, tubular-acinar dilation; atrophy and excess of fat deposition).
Up until now, comparable cell-based assays have only allowed the traCking of fast migrating cells such as neutrophiles or dictiostelia.

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