Neutrophil

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Related to neutrophilic: neutrophilic leukocytosis

neutrophil

[′nü·trə‚fil]
(histology)
A large granular leukocyte with a highly variable nucleus, consisting of three to five lobes, and cytoplasmic granules which stain with neutral dyes and eosin.

Neutrophil

 

(also called polymorphonuclear neutrophil leukocyte, microphage), a type of white blood cell, or leukocyte, occurring in vertebrates and man. The diameter of a neutrophil ranges from 9 to 12 μ. The cytoplasm of these cells contains granules that attract both basic and acidic dyes, and this is why these leukocytes are called neutrophils.

A neutrophil is classified according to its degree of maturity: a metamyelocyte is a young neutrophil with an unsegmented nucleus, a rod neutrophil has a nucleus in the shape of a curved rod, and segmented, or filamented, neutrophils have segmented nuclei. Neutrophils are phagocytes that are capable of ingesting small foreign particles, including microbes. By elaborating hydrolytic enzymes, neutrophils can lyse dead tissue. Neutrophilia is an abnormal increase in the concentration of neutrophils in the blood. (SeeLEUKOCYTOSIS.)

References in periodicals archive ?
A bullous neutrophilic dermatosis in a patient with severe rheumatoid arthritis and monoclonal IgA gammopathy.
1) Alper et al reported a case of neutrophilic dermatosis that occurred as a result of exposure to a radiocontrast agent.
Colchicine was particularly effective in patients with neutrophilic urticaria," the researchers noted.
The histological diagnosis of superimposed steatohepatitis was reported by the presence of hepatocellular ballooning degeneration and Mallory hyaline, mixed neutrophilic and lymphocytic intralobular infiltrate in addition to steatosis by hematoxylin and eosin (Fig.
Neutrophilic inflammation has been linked to steroid resistance in individuals with stable asthma, although the mechanisms for steroid resistance are not known.
Pyoderma gangrenosum (PG) is an uncommon ulcerative inflammatory disease, classified among the neutrophilic dermatosis.
The biopsy specimen of an actinomycetic infection shows a central neutrophilic lobulated abscess that contains a number of granules surrounded by granulation tissue.
Histological examination revealed multifocal intraepithelial neutrophilic aggregates (microabscesses) in the ruminal epithelium and diffuse autolysis of all sections of the intestines.
To the Editor: Sweet Syndrome (SS, acute febrile neutrophilic dermatosis) is a rarely seen disease that includes abruptly developing painful papullonodular or plaque-shaped erythematous lesions associated with systemic findings such as malaise, fever, arthralgia, conjunctivitis and episcleritis, and histologically characterized by edema on the upper dermis and intense neutrophilic infiltration.
Inhaled nitric oxide may modulate the acute neutrophilic inflammation of the lung parenchyma and dysfunction of the alveolar-capillary membrane that characterises acute respiratory distress syndrome.