nicotinamide


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nicotinamide

(nĭk'ətĭn`əmīd): see vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
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nicotinamide

[‚nik·ə′tin·ə‚mīd]
(biochemistry)
C6H6ON2 Crystalline basic amide of the vitamin B complex that is interconvertible with nicotinic acid in the living organism; the amide of nicotinic acid. Also known as niacinamide.
References in periodicals archive ?
Further, 'it would be worthwhile to determine whether nicotinamide would also be useful for high-risk melanoma patients', Halliday added.
A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention.
In the phase III ONTRAC trial, Australian investigators randomized 386 patients who averaged roughly eight nonmelanoma skin cancers in the past 5 years to either 500 mg of oral nicotinamide twice daily or matched placebo for 12 months.
The nicotinamide form does not generally cause flushing and is better tolerated than the nicotinic acid form.
The report provides a snapshot of the global therapeutic landscape for Nicotinamide Phosphoribosyl Transferase (NAmPRTase or Pre-B-Cell Colony-Enhancing Factor 1 or EC 2.
We gave nicotinamide riboside to 2-year-old mice, which is an advanced age for them," said the researcher.
A total of 386 immune competent participants with > 2 histologically-confirmed NMSC in the past 5 years were randomized (1:1) to oral nicotinamide 500 mg bd (NIC) or matched placebo (PBO) for 12 months.
Results reported in a press briefing held before the annual meeting of the American Society of Clinical Oncology showed that patients taking nicotinamide were about one-fourth less likely than peers taking a placebo to develop new basal cell and squamous cell skin cancers.
Nicotinamide is thought to help repair DNA in cells damaged by sun exposure.
investigated in vitro release of various drugs among which was nicotinamide, from silicone discs containing dispersed granules of interpenetrating polymer network (IPN) of poly(acrylic acid) and polyethylene oxide) loaded with drugs.
Streptozotocin (Keocyt, Val de Reuil, France), Nicotinamide (Sigma-Aldrich St Louis, MO, USA), PSO (Techno Parse Company, Tehran, Iran), and unpurified SBO (Animal Food Industry, Shiraz, Iran) were used.
Conversion to nicotinamide adenine dinucleotide was calculated by measuring oxygen at 340 nm for 10 minutes and comparing it to a standard curve.

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