nitric oxide synthase


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Related to nitric oxide synthase: Neuronal Nitric Oxide Synthase

nitric oxide synthase

[‚nī·trik ¦äk‚sīd ¦sin‚thās]
(biochemistry)
An enzyme that catalyzes the stepwise conversion of the amino acid L-arginine to nitric oxide and L-citrulline. There are three types: the brain (or neuronal) and epithelial nitric oxide synthases, which are always present in cells, and inducible nitric oxide synthase, which is produced as needed.
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References in periodicals archive ?
Chronic fetal hypoxia produces selective brain injury associated with altered nitric oxide synthases. Am J Obstet Gynecol 2011; 204: 16-28.
Vascular consequences of endothelial nitric oxide synthase uncoupling for the activity and expression of the soluble guanylyl cyclase and the cGMP-dependent protein kinase.
Inflammation, immunoregulation, and inducible nitric oxide synthase. J Leukoc Biol.
Caption: Figure 1: (a) Macroscopic wound findings of cutaneous excision wound healing in dorsal skin of inducible nitric oxide synthase (iNOS-) knockout (KO) mice and wild type (WT) mice.
Tanus-Santos, "Endothelial nitric oxide synthase: from biochemistry and gene structure to clinical implications of NOS3 polymorphisms," Gene, vol.
Kamogawa et al., "Repeated thermal therapy upregulates arterial endothelial nitric oxide synthase expression in Syrian golden hamsters," Japanese Circulation Journal, vol.
Fuchs et al., "Erratum: [Ca.sup.2+]/calmodulin-dependent nitric oxide synthase activity in the human cervix carcinoma cell line ME-180," Biochemical Journal, vol.
1,25-Dihydroxyvitamin D3 Induces Nitric Oxide Synthase and Suppresses Growth of Mycobacterium tuberculosis in a Human Macrophage-Like Cell Line.
Endothelial nitric oxide synthase overexpression attenuates myocardial reperfusion injury.
The association between endothelial nitric oxide synthase gene G894T polymorphism and hypertension in Han Chinese: a case-control study and an updated meta-analysis.
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.
The results of in vivo experiments showed that with increasing levels of dietary arginine, interleukin (IL)-2, NO content and inducible nitric oxide synthase (iNOS) activity in serum as well as iNOS mRNA expression in the ileum and liver of broiler chickens increasedquadratically at the age of 21 d(Pless than 0.05).In addition, positive effects of arginine tended to be suppressed when addition of arginine in the diet was increased to 18.0 g/kg.

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