nodular

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Related to nodular fasciitis: fibromatosis, myositis ossificans

nodular

[′näj·ə·lər]
(science and technology)
Occurring in the form of small, rounded lumps.
References in periodicals archive ?
Although there are no pathognomonic features radiologically, nodular fasciitis should be included in the differential diagnosis of a well-defined enhancing mass in a superficial and unusual location, especially in a young patient with a rapidly enlarging mass and a history of recent trauma to the area.
Nodular fasciitis in the head and neck: CT and MR imaging findings.
Nodular fasciitis of the head and neck: Radiographic findings.
Nodular fasciitis of the external ear masquerading as pleomorphic adenoma: A potential diagnostic pitfall in fine needle aspiration cytology.
The history alone is of little benefit in differentiating nodular fasciitis from other lesions, given its epidemiologic variability and its clinical similarity to other soft-tissue growths.
The high degree of histologic variation notwithstanding, all nodular fasciitis lesions do share some common features: (1) an overall proliferation of plump, spindle-shaped fibroblasts, (2) a serous (myxoid) ground substance, (3) a vascular component, (4) a minimal number of mononuclear cells, (5) occasional multinucleated giant cells, and (6) involvement of either superficial or deep fascia.
The nuclei seen in nodular fasciitis typically vary in size.
There are no reported characteristic CT or MRI findings to distinguish nodular fasciitis from similar but more aggressive lesions.
In a review of 6 cases, Shin et al found high variability in the radiologic appearance of nodular fasciitis.
The immunohistologic profile of nodular fasciitis is consistent.
Given the benign nature of nodular fasciitis, simple surgical excision is the treatment of choice.
In conclusion, recognizing the true benign nature of nodular fasciitis is important because it obviates the possibility that a patient will unnecessarily undergo aggressive treatment that might be performed on the basis of microscopic features that are suggestive of a malignancy.

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