nonsense suppression


Also found in: Medical.

nonsense suppression

[′nän‚sens sə‚presh·ən]
(genetics)
Suppression of the termination effect of a nonsense codon on a growing polypeptide chain, allowing return to the normal phenotype.
References in periodicals archive ?
The finding of improvement over placebo at the low dose of ataluren but not at the high dose is consistent with subsequent analysis of nonclinical data which suggest a bell-shaped dose response curve as a class-based effect for drugs that promote nonsense suppression.