nonsense suppression


Also found in: Medical.

nonsense suppression

[′nän‚sens sə‚presh·ən]
(genetics)
Suppression of the termination effect of a nonsense codon on a growing polypeptide chain, allowing return to the normal phenotype.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Genomic medicine is a prime example where a specific genetic mutation can be identified and a therapy can be applied that matches the exact defect, such as nonsense suppression therapy.
The finding of improvement over placebo at the low dose of ataluren but not at the high dose is consistent with subsequent analysis of non-clinical data which suggest a bell-shaped dose response curve as a class-based effect for drugs that promote nonsense suppression.