nordihydroguaiaretic acid


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nordihydroguaiaretic acid

[¦nȯr·dī¦hī·drō¦gwī·ə¦red·ik ′as·əd]
(organic chemistry)
C18H22O4 A crystalline compound with a melting point of 184-185°C; soluble in alcohols, ether, acetone, glycerol, and propyleneglycol; used as an antioxidant in fats and oils. Abbreviated NDGA.
References in periodicals archive ?
extract and nordihydroguaiaretic acid upon peroxidase secretion in rat submandibulary glands.
A cystic nephropathy induced by nordihydroguaiaretic acid in the rat.
Toxic properties of nordihydroguaiaretic acid. Food Cosmet Toxic 1968;6:155-61.
Medina-Campos et al., "Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozoneinduced tyrosine nitration in lungs," Free Radical Research, vol.
Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kvl.5 currents independently of lipoxygenase, Eur.
divaricata Cav is the nordihydroguaiaretic acid (NDGA) that is present on the external surface of the leaves (Mabry et al., 1977).
Also, a specific combination of OA and nordihydroguaiaretic acid (NDGA) derived from Larrea divaricata was found to reduce acne by reversing keratinocyte multiplication, reduce inflammation by inhibiting prostaglandin synthesis, and inhibit growth of yeast and bacteria, all of which prevented the onset of acne.

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