noscapine


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noscapine

[′näs·kə‚pēn]
(pharmacology)
C22H23NO7 A white, colorless, tasteless alkaloid obtained from opium; used as a nonaddicting antitussive.Formerly known as narcotine.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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EM012 (reduced C57BL/6J mice brominated derivative DSS of noscapine) (Isoquinoline) Derivative of noscapine, encountered in Papaver somniferum Fumigaclavine C BALB/c mice (Indole) TNBS Aspergillus fumigatus Hypaconitine Sprague-Dawley rats (Diterpenoid) TNBS Aconitum carmichaeli Isatin Wistar rats (Indole) TNBS Isatis sp., Calanthe discolor, Couroupita guianensis Matrine BALB/c mice (Quinolizidine) TNBS Sophora sp.
Keywords: Cinchonidine, cinchonine, quinine, noscapine, lipoxygenase, xanthine oxidase.
Singh, "Anticancer activity of Noscapine, an opioid alkaloid in combination with Cisplatin in human non-small cell lung cancer," Lung Cancer, vol.
Rezaei and Mirahmadi Zare dropped the suspension of multiwall carbon nanotubes (MWNTs) in nitric acid on the cleaned glassy carbon electrode (GCE) and then removed the acid to gain a modified glassy carbon with a high sensitivity to noscapine [6].
Scientists have long known how the plants make opiates such as codeine and morphine, but the molecular steps the plants use to make a non-addictive substance called noscapine have been a mystery until now.
In the late 1980s when the reaction occurred, papaveretum contained 47.5 to 52.5% morphine, 2.5 to 5.0% codeine, 16.0 to 20.0% narcotine (noscapine) and 2.5 to 7.0% papaverine (104).
The five major alkaloids are mainly divided into two distinct chemical classes (Reisine 1996:527)--phenanthrenes (morphine, codeine thebaine) and benzylisoquinolines (papaverine and noscapine).
We also use pharmaceutical agents with known anticancer activity, including COX-2 inhibitors such as Celebrex, Metformin, Noscapine, Disulfram, LDN (low-dose naltrexone), sodium phenylbutyrate, tetrathiomolybdate, and rapamycin, as well as Lupron, Casodex, Avodart, and Proscar.
Washington, Mar 20 (ANI): Cough medicine ingredient noscapine could be used as a prophylactic treatment for prostate cancer, according to a new study.
The Opium Poppy is the type of poppy from which opium and many refined opiates, including morphine, thebaine, codeine, papaverine, and noscapine, are extracted.
Genotoxicity evaluation of morphine, buprenorphine, pentazocine and noscapine by micronucleus assay & comet assay in mice.