Previously, the nuclear membrane
was thought to be mostly just a protective bubble around the nuclear material, with pores acting as channels to transport molecules in and out.
Some of the tumour cells had irregular nuclear membrane
and inconspicuous nucleoli.
This included disorganization of the cytoplasm and loss of organelles, a marked increase in the number and size of lysosomes, the disruption of plasma membranes, the loss of nuclear membranes
, nucleoli, and the fragmentation of condensed chromatin.
However, six amino acids were present only in the LMNA C type transcript, and these codons are important for binding to the inner nuclear membrane
via the C-terminal sequence in humans (Hennekes and Nigg, 1994).
Some of the typical features of apoptosis such as nuclear membrane
fragmentation and ladder-like DNA fragmentation was also observed after treating human melanoma cells with subfraction A or with compound 1.
It is mainly composed of nuclear lamina, which at the periphery, interacts with the inner nuclear membrane
and is interconnected with cytoskeleton at the pore complex.
However, in higher organisms, the nuclear membrane
breaks down during mitosis and the spindle is formed without constrains of the nuclear membrane
25) This means that the nuclear membrane
might have resulted from the membranes of the already-existing endoplasmic reticulum aggregating around the region that contains the genome (nucleoplasm).
The nuclear membrane
is smooth, and a large lacuna between the cell membrane and nuclear membrane
The nuclear membrane
appeared to still be intact and surrounded the nucleus, which was lacking in chromatin.
The nuclei showed that the chromatin was evenly dispersed, and there was a mild indentation of the nuclear membrane
Nascent particles were formed by the juxtaposition of viral nucleocapsids along cytoplasmic membranes of the budding compartment (the membrane region between the rough endoplasmic reticulum and the Golgi complex) or occasionally on the membranes of the rough endoplasmic reticulum that form the outer layer of the nuclear membrane