MR scanner is primarily used in conjunction with MRI hyperpolarization (Dynamic Nuclear Polarization
(DNP)), primarily based on the 13C nucleus but also on other cores.
It covers mechanisms of spin relaxation, the formal theory of spin relaxation, spin resonance lineshape analysis, how to describe spin relaxation phenomena in more complex systems accounting for different kinds of spin interactions, application of the theory to electron spin resonance spectra of nitroxide radicals, nuclear spin relaxation in paramagnetic fluids, spin resonance beyond perturbation range, dipolar relaxation and quadrupolar interactions, the effects of mutual spin interactions, dynamic nuclear polarization
, and anisotropic and internal dynamics.
Department of Energy's Ames Laboratory is now the home to a Dynamic Nuclear Polarization
(DNP) solid-state Nuclear Magnetic Resonance (NMR) spectrometer that helps scientists understand how individual atoms are arranged in materials.
Another 27 studies consider such topics as fluctuations and relaxation dynamics of liquid water revealed by linear and nonlinear spectroscopy, charge transport at the metal-organic interface, ultrafast photochemistry in liquids, single-molecule fluorescence imaging in living cells, dynamic nuclear polarization
methods in solids and solutions to explore membrane proteins and membrane systems, and molecular switches and motors on surfaces.
The second section offers 12 chapters on recent developments, including high-frequency dynamic nuclear polarization
, homonuclear and heteronuclear dipolar recoupling, and relaxation studies of solid biopolymers.
Dynamic nuclear polarization
(DNP) is a technique that increases the sensitivity of NMR experiments by increasing the polarization of the more rarely occurring nuclei in a given sample.
Its real part makes the neutron spin rotate around the direction of the nuclear polarization
5 T), only achieve very modest nuclear polarization
(less than 0.
Dynamic Nuclear Polarization
can enhance the sensitivity of solid-state NMR by approximately two orders of magnitude, by transferring polarization from the electron spins to the nuclear spins.
Focus is placed on two particular approaches, dynamic nuclear polarization
and para-hydrogen-driven polarization, exhibiting the highest potential for biophysical, metabolomic, pre-clinical and clinical research.
From the first come seven papers exploring conformational dynamics of oligosaccharides, structure and dynamics of carbohydrates using residual dipolar couplings, combined theoretical and NMR (nuclear magnetic resonance) experimental approach on carbohydrate-aromatic interactions and on pyranose ring distortion, laser photo chemically induced dynamic nuclear polarization
technique as a tool for structural analysis of inter- and intramolecular protein-carbohydrate interactions, and hydroxy protons in structural studies of carbohydrates by NMR spectroscopy.
At the polarization, the neutron and nuclear polarizations
are aligned in magnetic fields, while the neutron polarization must be aligned vertical to the nuclear polarization
for the measurement of the T-odd term.