nuclear transfer


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nuclear transfer

[′nü·klē·ər ′tranz·fər]
(cell and molecular biology)
Insertion of a diploid somatic nucleus into an egg from which the nucleus has been removed.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Epigenetic reprogramming in embryonic and foetal development upon somatic cell nuclear transfer cloning.
Table I.- Effect of different exogenous Npm or PGA on the efficiency of BMI somatic cell nuclear transfer.
Table 3.Effect of frozen PZM3 on the in vitro development of porcine somatic cell nuclear transfer embryos.
For their comparisons, the researchers at San Diego, OHSU and Salk created four nuclear transfer ES cell lines and seven iPS cell lines using the same skin cells as the source of donor genetic material, then compared them to two standard human ES lines.
Prather, "Clonal lines of transgenic fibroblast cells derived from the same fetus result in different development when used for nuclear transfer in pigs," Biology of Reproduction, vol.
Animal cloning: the science of nuclear transfer. 1st ed.
"While nuclear transfer breakthroughs often lead to a public discussion about the ethics of human cloning, this is not our focus, nor do we believe our findings might be used by others to advance the possibility of human reproductive cloning."
Nuclear transfer protocol affects messenger RNA expression patterns in cloned bovine blastocysts.
This book explains recent work in human myoblast genome therapy, or HMGT (previously known as myoblast transfer therapy, or MTT), a platform technology of cell transplantation, nuclear transfer, and tissue engineering.
The scientists, led by Dr TeruhikoWakayama, of Kobe, Japan, wrote: "We have demonstrated here that healthy cloned mice could be obtained by nuclear transfer using donor nuclei from cells obtained from bodies frozen without cryoprotectants for up to 16 years."
What is somatic cell nuclear transfer? Nuclear transfer refers to the removal of a nucleus, which contains the genetic material, from virtually any cell of the body (a somatic cell) and its transfer by injection into an unfertilised egg from which the reconstituted nucleus has been removed.

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