nucleocapsid

(redirected from nucleocapsids)
Also found in: Dictionary, Medical.

nucleocapsid

[¦nü·klē·ō′kap·səd]
(virology)
The nucleic acid of a virus and its surrounding capsid.
References in periodicals archive ?
Particles are composed of a tangle of nucleocapsids enclosed within the viral envelope, which contains surface projections 12 nm in length (Figure 1, panel C).
Nucleocapsids appeared to be angular and surface capsomer arrangement obvious.
Filamentous structures morphologically similar to viral nucleocapsids in otosclerotic lesions in two patients.
8 nm) and did not resemble the more thread-like nucleocapsids of influenza virus.
These IFN-stimulated genes inhibit viral replication by many different mechanisms, including binding to viral nucleocapsids, translation inhibition, RNA degradation, RNA editing, and apoptosis induction.
Cleavage of the HA0 protein of influenza viruses results in an essential confonnational change in the HA protein, which enables the envelope of the endocytosed virus to fuse with the membrane of endosomes, releasing nucleocapsids into the cytoplasmic compartment (5,13).
Once internalized, the virus core uncoats, revealing flattened, disc-shaped, and electron-dense nucleocapsids described as "doughnut-shaped" (10,11).