nucleophilic displacement

nucleophilic displacement

[‚nü·klē·ə¦fil·ik di′splās·mənt]
(organic chemistry)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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The presence of the corresponding acyclic intermediates 229 could be confirmed by means of [sup.1]H NMR spectroscopy, implying that the formation of benzothiazepines 230 proceeds through initial attack of the sulfur atom of o-aminothiophenol onto the less hindered aziridine carbon atom, followed by nucleophilic displacement of bromide by the amino group.