nucleophilic substitution


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nucleophilic substitution

[‚nü·klē·ə¦fil·ik ‚səb·stə′tü·shən]
(organic chemistry)
A reaction in which a nucleophile bonds to a carbon atom in a molecule, displacing a leaving group. Also known as nucleophilic displacement.
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Based on the product, the global polyetherketone market is segmented as: Electrophilic substitution Nucleophilic substitution Based on the application, the global polyetherketone market is segmented as: Machine parts Nuclear power-plant equipment Automobile parts Aerospace components Cable insulation Pump parts Others Nucleophilic substitution polyetherketone is anticipated to showcase remarkable growth rate during the forecast period due to its wide scale application.
Among their topics are addressing the challenges of stand-alone multi-core simulations in molecular dynamics, an analytical solution of the pantograph equation with incommensurate delay, the mechanism of nucleophilic substitution reactions of 4-(4'-nitro) phenylnitrobenzofurazan ether with aniline in acetonitrile, computational methods in pre-formulation study for pharmaceutical solid dosage forms of therapeutic proteins, and elemental two-dimensional materials beyond graphene.
The nucleophilic substitution attack of nitrogen nucleophile of propargylamine on the exocyclic methylene center provided corresponding substitution products (30a-e).
The [sup.18]F-isotope was introduced on the bile acid skeleton by a nucleophilic substitution on a suitable mesylate, protected precursor molecule of which the synthesis can be found in Supplementary Data (available).
This reaction involves nucleophilic substitution in bromothiazole followed by nucleophilic substitution on the ester group to form the pyrimidinone ring (compounds 3a-b).
These results suggest that the nucleophilic substitution reaction between covalent bonds (Si-O) of nano-ppy/OMMT and HF derived from LiP[F.sub.6] can move and bend [37, 38].
This structure easily undergoes nucleophilic substitution with water.
Biphenyl analogues were synthesized by using general synthetic route involving nucleophilic substitution reactions on functional biphenyl analogues.
The sulfonated poly(aryl ether sulfone) copolymers (SPSFs) with different DS were synthesized via an aromatic nucleophilic substitution copolymerization of two different bisphenol (BPA and PhBPA) monomers, various ratios of disulfonated monomers (SDCDPS, monomer x) to nonsulfonated monomers (DCDPS, monomer 100-x) and 1.2 mole ratios of [K.sub.2]C[O.sub.3] in a N-methyl-2-pyrrolidone (NMP)/toluene solvent system (as shown in Scheme 1).