nucleotide excision repair


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nucleotide excision repair

[¦nü·klē·ə‚tīd ik′sizh·ən rē‚per]
(cell and molecular biology)
A five-step pathway that is the major repair system for removing bulky lesions in deoxyribonucleic acid.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis.
Therefore, a variety, of DNA repair processes such as the base excision repair (BER), nucleotide excision repair (NER), and mismatch and double-strand break repairs have evolved to perform the critical repair functions (Dybdahl et al.
Two postdoctoral positions are available to study how nucleotide excision repair proteins recognize and process DNA damage.
Wang et al., "Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients," Cancer Research, vol.
The reaction is common and is usually quickly repaired by nucleotide excision repair [8].
Excision repair, which includes base excision repair (BER) and nucleotide excision repair (NER), is a complex multistep pathway, where the damaged DNA is replaced with a new one and plays an important role in DNA repair with the help of a number of glycosylases and polymerases, respectively (Figure 1) [72].
What's more, this technique is not limited to reading damage caused by BPDE, but can be used for any type of DNA damage that uses something called nucleotide excision repair.
Known as nucleotide excision repair, it involves the recruitment of special proteins that perform DNA surgery.
Xeroderma Pigmentosum (XP) is a rare autosomal recessive disorder, first described by Hebra and Kaposi in 1874, which is caused by a defective nucleotide excision repair (NER) system, which produces mainly skin, ocular, and neurologic alterations [1, 2].
Li, "Laryngeal cancer risk and common single nucleotide polymorphisms in nucleotide excision repair pathway genes ERCC1, ERCC2, ERCC3, ERCC4, ERCC5 and XPA," Gene, vol.
UVC irradiation or numerous carcinogenic chemicalscaused DNA adducts are repaired by nucleotide excision repair (NER).