2005) BCL11B functionally associates with the
NuRD complex in T lymphocytes to repress targeted promoter.
Cellartis AB, Cellectis Stem Cells, will provide human embryonic stem cells (hESCs) to the program and will be involved in the development of methodologies for large scale proteomic analysis of the PRC and
NuRD complexes during cell differentiation.
One of the disadvantages of these systems is their susceptibility to
NURD (non-uniform rotational distortion), which may cause imaging and measurement inaccuracies.