ochronosis


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ochronosis

[‚ō·krə′nō·səs]
(medicine)
A blue or brownish-blue discoloration of cartilage and connective tissue, especially around joints, caused by melanotic pigment.
References in periodicals archive ?
Ochronosis is a syndrome caused by the accumulation of homogentisic acid (HGA) in connective tissues.
Black colored intervertebral disc; ochronosis: A case report
It has been suggested that the delayed appearance of ochronosis is associated with decreased renal clearance of HGA with aging.
Multiple Arthroplasty in a Patient with Alkaptonuric Arthritis
Ochronosis is a rare metabolic disorder that affects peripheral joints as well as spine and soft tissue.
Patients with black hip and black knee due to ochronotic arthropathy: case report and review of literature
2), (3) Furthermore, in this disease, excessive HGA is converted to a polymeric melanin-like pigment that binds to all connective tissues in a pathophysiological process called ochronosis.
A previously undiagnosed case of alkaptonuria: a case report: daha once tani konulmamis alkaptonuri: olgu sunumu
However, in cases of significant degenerative arthritis, joint replacement can be performed with anticipation of outcomes comparable to osteoarthritic patients without ochronosis.
Degenerative arthritis of the knee secondary to ochronosis: a case report
Ochronosis of prostate presenting as advanced carcinoma.
Blue nevus of the prostate
It is well known that use of mercury or excessive hydroquinone in skin care products have resulted in serious health complications and skin rash known as ochronosis.
Good skin tone remains a global beauty attribute
We report the case of a male patient, aged 40 years, with knee and lumbar spine arthropathy secondary to confirmed ochronosis.
Espondiloartropatia ocronotica: reporte de un caso
Other rare causes of AS includes: Subacute Lupus Erythematosus (SLE), rheumatoid arthritis, homozygous type II hyperlipidemia, Paget's disease, infective endocarditis, ochronosis and radiation.
Aortic valvular heart disease in the adults
While exogenous ochronosis is seen in about 42% of South African women and 15% of South African men using hydroquinone, the condition is very rare in the United States.
Result of pregnancy, OC use: melasma misconceptions may impede treatment
Localized exogenous ochronosis (blue-black hyper pigmentation) of the face developed in a fifty year-old black woman who had used a proprietary bleaching cream containing 2% hydroquinone up to six times daily for about two and half years.
An epidemiological survey on the presence of toxic chemicals in soaps and cosmetics used by adolescent female students from a Nigerian University
Among the possible causes of black thyroid are minocycline-induced pigmentation, hemochromatosis, ochronosis, mucoviscidosis, ceroid storage disease, bruising, and hemorrhage.
Black thyroid
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