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Related to ocular histoplasmosis: presumed ocular histoplasmosis


see fungal infectionfungal infection,
infection caused by a fungus (see Fungi), some affecting animals, others plants. Fungal Infections of Human and Animals

Many fungal infections, or mycoses, of humans and animals affect only the outer layers of skin, and although they are sometimes
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a fungal disease (mycosis) that attacks primarily the reticuloendothelial system in man and animals.

Histoplasmosis is found mostly in tropical countries. The causative agent is the parasitic fungus Histoplasma, which can survive for long periods in soil. There is no direct indication that histoplasmosis is transmitted from one person to another; it may be transmitted by mites. It occurs in acute, subacute, chronic, disseminated, or localized forms. Histoplasmosis is manifested by enlargement of the liver, spleen, and lymph nodes, fever, and anemia. It involves the skin and mucous membranes (hemorrhages and occasionally ulcerative lesions) in half the patients. Bloody expectoration occurs in pulmonary histoplasmosis. Supportive and radiation therapy, medication, and surgical intervention are used in treatment.


An infectious fungus disease of the lungs of humans caused by Histoplasma capsulatum.
References in periodicals archive ?
Association of the HLA-DR15/HLA-DQ6 haplotype with development of choroidal neovascular lesion in presumed ocular histoplasmosis syndrome.
Which of the following statements about Presumed Ocular Histoplasmosis Syndrome (POHS) is TRUE?
Dan Myers, president of Novartis Ophthalmics, North America said, "The fact that Visudyne therapy has demonstrated the ability to stabilize and in some cases improve vision in these pathologic myopia and presumed ocular histoplasmosis patients is another remarkable success story for this breakthrough therapy.
Presumed ocular histoplasmosis syndrome (POHS) was first described in 1959 by Woods and Wahlen (1) as peripheral chorioretinal scar and hemorrhagic macular disciform lesion in a patient with positive histoplasmin skin test.
These cases were diagnosed with myopia, punctate inner choroidopathy (PIC), presumed ocular histoplasmosis syndrome (POHS) and idiopathic CNV (37,38,39)