Esophagitis

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Related to oesophagitis: Reflux oesophagitis, hiatus hernia

esophagitis

[ə‚säf·ə′jīd·əs]
(medicine)
Inflammation of the esophagus.

Esophagitis

 

inflammation of the mucosa of the esophagus. Esophagitis may be an independent disease or, more often, a symptom of another disease of the esophagus, stomach, or other organ. The inflammation is frequently caused by chemical, mechanical, or thermal irritation of the esophagus; for example, it may be caused by eating very hot and spicy food.

Catarrhal, phlegmonous, necrotic, and other forms of esophagitis are distinguished based on the severity of the inflammatory changes. In severe cases the inflammatory process may extend to the muscular layer of the esophagus, and sometimes, to the surrounding mediastinal tissue, giving rise to mediastinitis. One form of the disease, peptic esophagitis, is caused mostly by a reflux of the acidic contents of the stomach into the esophageal lumen in cases of hiatus hernia. Peptic esophagitis is sometimes associated with the development of an ulcer in the esophageal wall.

The course of the disease may be acute or chronic. Chronic esophagitis is frequently caused by alcohol abuse or smoking. The symptoms include a burning sensation, retrosternal pain on swallowing, excessive salivation, and regurgitation of food. Esophagoscopy is sometimes used to diagnose the disease. Treatment is by diet (eliminating coarse, hot, and acidic foods), pain relievers, astringent and antispasmodic drugs, and, in some forms, antibiotics and surgery.

REFERENCE

Vasilenko, V. Kh., A. L. Grebnev, and M. M. Sal’man. Bolezni pishchevoda. Moscow, 1971.

I. V. IAREMA

References in periodicals archive ?
A range of toxicities were reported including acute fatigue, acute cough, acute oesophagitis, radiation pneumonitis, dermatitis, musculoskeletal discomfort, pneumonia, pleural effusion, apnoea, brachial plexopathy, partial arm paralysis and skin reactions [23, 40, 41].
Non ulcer dyspepsia (47%) was the commonest diagnosis followed by peptic ulcers (42%) and reflux oesophagitis (10%).
Introduction: Eosinophilic oesophagitis (EoE) is a chronic antigen-driven inflammatory disease characterised histologically by high levels of eosinophils in the oesophagus and clinically by oesophageal dysfunction and gastrointestinal (GI) symptoms.
Eradication of Helicobacter pylori does not increase acid reflux in patients with mild to moderate reflux oesophagitis. Scand J Gastroenterol 2002;37:877-83.
Comparison of histological parameters for the diagnosis of eosinophilic oesophagitis versus gastroesophageal reflux disease on oesophageal biopsy material.
Transient relaxation of the lower oesophageal sphincter (LES) is an important cause of reflux events both in normal individuals and in patients with oesophagitis. Newer evidence suggests that the frequency of these transient relaxations is not higher in GERD patients than normal, but when relaxations do occur, they are more likely to be associated with reflux of acid in GERD patients.11 Few episodes of reflux are due to abrupt increases in intra-abdominal pressure that overcomes LES pressure.
[3,5] Doxycycline is an acidic drug and due to its acidic nature it can cause a focal contact oesophagitis followed by oesophageal ulcers.
Barrett, "Chronic peptic ulcer of the oesophagus and 'oesophagitis?' The British Journal of Surgery, vol.
Rosaida, "Time trends in peptic ulcer, erosive reflux oesophagitis, gastric and oesophageal cancers in a multiracial Asian population," Alimentary Pharmacology and Therapeutics, vol.
[17] state that the causes of bolus impaction in the oesophagus are eosinophilic oesophagitis and reflux oesophagitis with and without peptic stenosis.
For example, a review of 7 core European and Australasian surgical textbooks reveals that only 3 textbooks make reference to hiatus hernias being a cause of bleeding or anaemia, and, in these books, bleeding is chiefly attributed to reflux oesophagitis [20-26].
In addition, side-effects such as nausea and vomiting, skin irritations and oesophagitis have been observed.