Estriol

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estriol

[′e‚strī‚ȯl]
(biochemistry)
C18H24O3 A crystalline estrogenic hormone obtained from human pregnancy urine.

Estriol

 

C18H24O3, a female sex hormone of the estrogen group with the chemical formula

Estriol occurs as colorless crystals with a melting point of 280°C. It is readily soluble in organic solvents. Optically active, it has a specific rotation of [α]D = +61°. Estriol was first isolated in 1934 from the urine of pregnant women. The hormone is ten to 15 times weaker in its physiological activity than estrone, from which it may be easily obtained semisynthetically.

In humans, dogs, and rats, estriol is one of the end products of the metabolism of estrogen. Estriol has also been discovered in the fruits and flowers of certain plants, including the willow, milkweed, and wheat. Seasonal changes or unusual local conditions sometimes cause an increase in the amount of the hormone contained in forage grasses. As a result, cattle may suffer from certain diseases or may produce less milk, since estriol inhibits lactation. Estriol has important physiological functions (see).

References in periodicals archive ?
Used in conjunction with the biochemical markers across first and second trimester and factoring maternal age, the combination of nuchal translucency, PAPP-A, maternal serum AFP, unconjugated oestriol, phCG and inhibin-A gave a 93% detection rate with a false positive rate of 2.6% (37).
Components include the natural oestrogens oestradiol, oestrone and oestriol, plus oestrogens from the urine of pregnant mares.
The influence of smoking on intrauterine fetal growth and maternal oestriol excretion.
Oestrogen appears in three forms in circulation-oestradiol, oestrone, oestriol. LH surge leading to ovulation can occur only in the presence of excess oestradiol in the serum.
BHT is the use of hormones identical to those secreted in the ovary or adrenal gland, namely oestradiol, oestrone, oestriol, dehydro-epiandrosterone (DHEA) and testosterone.
EXERCISE converts one of our weak male hormones to the weak female hormone, oestriol, but every little helps, so every menopausal woman should exercise.
The levels of human chorionic gonadotropin, unconjugated oestriol and alpha-fetoprotein (triple markers) are significantly lower in pregnancies with trisomy 18 compared to normal pregnancy.
Oestrogen antagonisms: the effects of oestriol and 16-epi-oestriol on oestrone-induced uterine growth in spayed rats.