esthesioneuroblastoma

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esthesioneuroblastoma

[es¦thē·zē·ō¦nu̇r·ō‚bla′stō·mə]
(medicine)
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9%) of melanoma and sinonasal lymphoma each and one case of olfactory neuroblastoma (2.
We retrieved 36 cases of Olfactory neuroblastoma from the surgical pathology database of Section of Histopathology, Aga Khan University Hospital reported between January 1993 and December 2014 through "Integrated Laboratory Management System (ILMS)" software.
Hyams Grading System for Olfactory Neuroblastoma Lobular Architecture Nuclear Grade Preservation Mitotic Index Pleomorphism I Present Zero None II Present Low Low III May or may not be present Moderate Moderate IV May or may not be present High High Grade Fibrillary Matrix Rosettes Necrosis I Prominent HW rosettes None II Present HW rosettes None III Low FW rosettes Rare IV Absent None Frequent Abbreviations: FW, Flexner-Wintersteiner; HW, Homer-Wright.
Olfactory neuroblastoma (ONB) is a malignant neoplasm thought to arise from the olfactory membrane of the sinonasal tract.
The second opinion was that the specimens represented an invasive, poorly differentiated NEC, probably a large-cell variant, with the differential diagnosis lying at a point somewhere between poorly differentiated large-cell NEC and high-grade olfactory neuroblastoma.
The final histopathological examination also confirmed the tumor as olfactory neuroblastoma.
Olfactory Neuroblastoma 01 01% Table 6: Incidence of Neoplastic and Non neoplastic lesion Sl.
One of the characteristic radiographic findings of olfactory neuroblastoma is a dumbbell-shaped mass that extends across the cribriform plate; erosion of the cribriform plate, lamina papyracea, and/or fovea ethmoidalis may also be seen.
The symptoms of olfactory neuroblastoma include unilateral progressive nasal obstruction, rhinorrhoea, epistaxis, anosmia and headache.
Fig1] in the field, reported as possible olfactory neuroblastoma.
However, there is a broad histologic differential diagnosis, which includes melanoma, rhabdomyosarcoma, lymphoma, olfactory neuroblastoma, Ewing's sarcoma, and primitive neuroectodermal tumors.
INTRODUCTION: Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare neoplasm originating from olfactory neuroepithelium in the superior portion of the nasal cavity.