This was especially true of less-developed primitive oligodendrocyte
Total RNA was extracted from BMSC, oligoprogenitor and oligodendrocyte
cells using RNX Plus TM (Cinnagen, Iran).
The structure and function of myelin oligodendrocyte
The current study for the first time showed that 9-cis-RA might induce the differentiation of NSCs into oligodendrocytes
via more or less the same mechanisms as [T.sub.3], while 1,25[(OH).sub.2][D.sub.3] was less potent in oligodendrocyte
differentiation compared to 9-cis-RA and evidently acted through different mechanisms.
Citation: Mayur Madhavan et al., Induction of myelinating oligodendrocytes
in human cortical spheroids.
Zeka et al., "Human antibodies against the myelin oligodendrocyte
glycoprotein can cause complement-dependent demyelination," Journal of Neuroinflammation, vol.
In a rat model of compressive SCI, treatment with ChABC promoted oligodendrocyte
differentiation and myelination of endogenous and transplanted neural precursor cells [173, 174].
The cells would be converted into oligodendrocytes
and returned to that individual to repair damaged neurons without risking rejection as foreign cells.
We thought it would be important to establish the temporal evolution of microglia activation, astrocytosis, oligodendrocyte
damage, and Nogo-A immunoreactivity during the first month after ET-1-induced stroke, as a morphological basis for further functional studies seeking new neuroprotective drugs.
In the present study, apoptosis and cell viability in the condition of ERS, activating transcription factor 4 (ATF4) (UPR biomarker) and light chain 3 (LC3) turnover (marker of autophagy) were detected in human oligodendrocyte
cell line transfected with missense, deletion or truncated mutations that influence eIF2B?
AST-OPC1, an oligodendrocyte
progenitor population derived from human embryonic stem cells, has been shown to have three potentially reparative functions that address the complex pathologies observed at the SCI injury site.
The finding, which they demonstrated in rats and cultured rat brain cells, suggests a key role for oligodendrocytes
in long-term and perhaps permanent changes in the brain that could set the stage for later mental problems.