oligodendrocyte


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oligodendrocyte

[äl·i·gō′den·drə‚sīt]
(neuroscience)
Glial cell responsible for elaborating myelin in the central nervous system.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive ?
This was especially true of less-developed primitive oligodendrocyte progenitor cells.
Total RNA was extracted from BMSC, oligoprogenitor and oligodendrocyte cells using RNX Plus TM (Cinnagen, Iran).
The current study for the first time showed that 9-cis-RA might induce the differentiation of NSCs into oligodendrocytes via more or less the same mechanisms as [T.sub.3], while 1,25[(OH).sub.2][D.sub.3] was less potent in oligodendrocyte differentiation compared to 9-cis-RA and evidently acted through different mechanisms.
Citation: Mayur Madhavan et al., Induction of myelinating oligodendrocytes in human cortical spheroids.
Zeka et al., "Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination," Journal of Neuroinflammation, vol.
In a rat model of compressive SCI, treatment with ChABC promoted oligodendrocyte differentiation and myelination of endogenous and transplanted neural precursor cells [173, 174].
The cells would be converted into oligodendrocytes and returned to that individual to repair damaged neurons without risking rejection as foreign cells.
We thought it would be important to establish the temporal evolution of microglia activation, astrocytosis, oligodendrocyte damage, and Nogo-A immunoreactivity during the first month after ET-1-induced stroke, as a morphological basis for further functional studies seeking new neuroprotective drugs.
In the present study, apoptosis and cell viability in the condition of ERS, activating transcription factor 4 (ATF4) (UPR biomarker) and light chain 3 (LC3) turnover (marker of autophagy) were detected in human oligodendrocyte cell line transfected with missense, deletion or truncated mutations that influence eIF2B?
AST-OPC1, an oligodendrocyte progenitor population derived from human embryonic stem cells, has been shown to have three potentially reparative functions that address the complex pathologies observed at the SCI injury site.
The finding, which they demonstrated in rats and cultured rat brain cells, suggests a key role for oligodendrocytes in long-term and perhaps permanent changes in the brain that could set the stage for later mental problems.