oligodendroglioma


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oligodendroglioma

[‚äl·ə·gō·den‚dräg·lē′ō·mə]
(medicine)
A slowly growing, large, well-defined cerebral glioma, composed of small cells with richly chromatic nuclei and scanty, poorly staining cytoplasm.
References in periodicals archive ?
Similarly, a tumor that is positive for IDH1 mutation, that is positive for ATRX (indicating intact expression), and that demonstrates a wild-type pattern of p53 expression, should prompt further assessment for 1p/19q deletional status in the presence of any oligodendroglial morphologic characteristics (or potentially even in their absence) to support or deny the designation of oligodendroglioma.
20% of oligodendrogliomas can have mass effect and calcification which are not common in astrocytomas.
Tumor n Craniopharyngioma 8 Meningioma, grade I-II 59 Glioblastoma 60 Astrocytoma, grade I-II 35 Astrocytoma, grade III 7 Ependymoma, grade I-II 14 Ependymoma, grade III 3 Oligodendrogliomas, grade II 7 Oligodendrogliomas, grade III 1 Mixed glioma (oligoastrocytomas), grade III 3 Carcinoma (metastatic) 20 Medulloblastoma 18 Lymphoma 3 Schwannoma 3 Choroid plexus papilloma 6 Central neurocytoma 4 Primitive neuroectodermal tumor (PNET) 3 Atypical teratoid/rhabdoid tumor 4 Hypothalamic hamartoma 3 Table 4: Cases in which there were discrepancies between the frozen section report and the final diagnosis (based on permanent section).
The boy underwent burr hole procedure and biopsy was taken from right parietal lobe by a neurosurgeon and was sent for histopathology which revealed "Anaplastic Oligodendroglioma grade 3.
Long-term prognosis was best for patients with oligodendrogliomas and all other tumours, and poorest for patients with GBM.
Specifically, NBTS is seeking applications in areas of biomarker research that can advance the understanding of oligodendroglioma tumors as well as therapeutic development and patient care, including prognostic biomarkers that can predict patient survival; predictive biomarkers that can identify patients who are most likely to benefit from investigational therapies and guide drug development; and surrogate biomarkers to predict patient outcomes based on response to treatment.
Medical and Demographic Characteristics for Patients (N = 30) Gender Male/female 19/11 Age: median (range) 60 (29-82) Diagnosis Glioblastoma multiforme, WHO grade IV 23 Primitive neuroectodermal, tumor 1 WHO grade IV Gliosarkoma, WHO grade IV 1 Anaplastic astrocytoma, WHO grade III 4 Anaplastic oligodendroglioma, 1 WHO grade III Surgical procedure Operation/biopsy 23/7 Unifocal/multifocal 18/12 Marital status Married/living with partner 24 Single/divorced/living alone 6 Children living at home 9 Baseline BMI: mean (range) 26.
Mackenzie JM, Franks AJ, Vanhille PT, Cameron MM, The evolution of an oligodendroglioma into a primitive neuroectodermal tumour, Neuropathol Apple Neurobiol, 1988;14, 71-79.
9 4 4 0 n/a >40 3 2 1 n/a Total 108b 89 19 n/a Brain tumor pathology (c) Acoustic neuroma 1 1 0 n/a Amyloidoma 2 1 1 n/a Astrocytoma (d) 6 4 2 n/a Carcinoma (e) 9 5 4 n/a Chordoma (e) 1 1 0 n/a CPA tumour 1 1 0 n/a Glioblastoma 27 21 6 n/a multiforme (e) Hemangioblastoma 4 3 1 n/a Lymphoma (e) 1 0 1 n/a Meningioma 39 38 1 n/a Neurocytoma 1 1 0 n/a No pathology 4 3 1 n/a Oligodendroglioma (d) 1 1 0 n/a Pituitary tumour 8 7 1 n/a Schwanomma 1 1 0 n/a Seminoma (e) 1 0 1 n/a Subependyoma 1 1 0 n/a Teratoid rhaboid 1 1 0 n/a tumour (e) Total 109 90 19 (a) Combined comparison: [chi square] between SGA-A versus combined categories ofSGA-B, and SGA-C (SGA, subjective global assessment).
Neoplasmas que ocorrem nas cavidades ventriculares, tais como, carcinoma de plexo coroide e ependimoma, alem de outros tumores SNC, como astrocitoma, oligodendroglioma, meduloblastoma devem ser incluidos no diagnostico diferencial (KOESTNER & HIGGINS, 2002).
In the grade III glioma subgroup, 2 patients were affected by anaplastic oligodendroglioma and 4 patients by anaplastic astrocytoma; in the grade IV glioma subgroup all patients were affected by glioblastoma.