oncofetal antigen


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oncofetal antigen

[¦aŋk·ə‚fēd·əl ′ant·i·jən]
(immunology)
Any of a group of antigens that are commonly present both in fetal tissue during early development of life and in adult tissue when cancer occurs.
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Menegola et al., "Sperm Protein17 is an oncofetal antigen: A lesson from a murine model," International Reviews of Immunology, vol.
Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3.
"The results of this preclinical work with ADXS-HOT represent an exciting opportunity that may allow us to develop disease-specific immunotherapies that have the potential to be effective against multiple targets, capable of generating high-avidity T cells against shared of public mutations, as well as multiple proprietary highly immunogenic cancer-testes and oncofetal antigens for multiple tumor types," said Robert G.
Two of the analytes examined, CA15-3 and CA125, showed atypical patterns of expression during the first year of life given their suspected status as oncofetal antigens (Fig.