oncogenesis


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Related to oncogenesis: carcinogenesis

oncogenesis

[¦äŋ·kō′jen·ə·səs]
(medicine)
Processes of tumor formation.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
(1,17) This finding highlights the importance of the cell of origin in the oncogenesis of different entities with recurrent gene fusions, (4) a concept perhaps best illustrated by the recurrent ETV6-NTRK3 gene fusions across biologically distinct tumors of epithelial, mesenchymal, and hematopoietic differentiation (secretory carcinoma, infantile fibrosarcoma, and acute myeloid leukemia, respectively).
NSD1 mutation has recently been linked to the blocking of cellular differentiation and the promotion of oncogenesis in this type of tumor.
Alongside Weinberg, Bargmann examined the molecular mechanisms of oncogenesis, helped identify the role of Ras in bladder cancer, and discovered a mutated gene that ultimately became the foundation of the breast cancer drug Herceptin.
Debnath, "Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures," Annu Rev Pathol, vol.
Failed regulation of both types of miRNAs promotes oncogenesis, proliferation and invasion of cancer cells, and the epithelial-mesenchymal transition (EMT).
Despite their mysterious origin, intergenically spliced chimeric RNAs are found across tissue types and have proven importance in normal cell states [2, 3, 5, 8] as well as demonstrated roles in both oncogenesis and cell differentiation.
The incidence of AIN with nonrenal cancer [11,12] indicates that the presence of underlying renal oncogenesis is not associated with AIN.
MYB driver mutations associated with oncogenesis have been confirmed in several types of malignancies including leukemias and adenoid cystic carcinomas [21].
For gliomas, which represent 75% of all malignant brain tumors, N-acetylaspartate (NAA) and 2-hydroxyglutarate (2HG) are markers of oncogenesis, and their MS measurement in brain tissue has the potential to improve glioma diagnosis.
There is data to suggest that poor dental health results in alteration in the oral flora and this may well play an etiological role in oncogenesis through an inflammatory process.
Being the first disease to correlate cancer and viral infection, EV serves as the cornerstone of the understanding of viral oncogenesis. We report three cases of EV, of which one patient subsequently developed Bowen's disease.