ookinete


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ookinete

[‚ō·ə′kī‚nēt]
(invertebrate zoology)
The elongated, mobile zygote of certain Sporozoa, as that of the malaria parasite.
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References in periodicals archive ?
Ookinete destruction within the mosquito midgut lumen explains Anopheles albimanus refractoriness to Plasmodium falciparum (3D7A) oocyst infection.
During this phase, it is possible to interrupt the fertilization process and ookinete invasion to the mosquito's intestinal cells, preventing development of the parasite within the mosquito and, hence, its transmission to other susceptible individuals (14).
Anti-vector transmission-blocking vaccines inhibit parasite development by preventing ookinete Interaction with mosquito midgut ligands.
More significantly, this study discovered the Imd pathway signal transducing factors and effectors that will mediate a successful reduction of parasite infection at their early ookinete stage, as well as in the later oocyst stage when the levels of infection were similar to those found in nature.
Cryofracture electron microscopy of the ookinete pellicle of Plasmodium gallinaceum reveals the existence of novel pores in the alveolar membranes.
Plasmodium gallinaceum: a refractory mechanism of ookinete killing in the mosquito, Anopheles gambiae.
AZT might interfere with transmission by exoerythrocytic inhibition of parasite liver stages in humans and mice (3) and by interference with ookinete and sporozoite production in mosquitoes (4).
Plasmodium vivax ookinete surface protein Pvs25 linked to cholera toxin B subunit induces potent transmission-blocking immunity by intranasal as well as subcutaneous immunization.
During the ookinete life stage, the parasite links to these receptors as it migrates to the salivary glands.
Successful development includes exflagellation, fertilization, ookinete formation, and penetration through the peritrophic matrix and midgut epithelium to form oocysts.
Two types of Plasmodium ovale defined by SSU rRNA have distinct sequences for ookinete surface proteins.
vivax also has O-type genes, which are expressed during ookinete and oocyst development.