First, to our knowledge, the bilateral occurrence of such lesions is extremely rare with only 2 bilateral cases previously reported: 1 case with bilateral gonorrheal ophthalmia neonatorum
, (3) and another involving the optic nerves bilaterally and thought to be due to a congenital anomaly.
40 `would avert one case of gonoccal ophthalmia neonatorum
The most serious consequence of gonorrhea and chlamydia in pregnant women is the occurrence of ophthalmia neonatorum
, a severe eye infection that can cause blindness in newborns.
When Erythromycin Ophthalmic Ointment was in short supply in 2009, the CDC recommended the use of another brand of gentamicin ophthalmic ointment that contains preservatives, as an alternative treatment for the prophylaxis of ophthalmia neonatorum
DISCUSSION: Ophthalmia neonatorum
is the most common ocular disease in the newborn, occurring in 2-12% (3,4,5) of neonates.
For example, two of the leading causes of blindness and visual impairment in the United States in the early 1900s were ophthalmia neonatorum
He was admitted to the hospital for presumed ophthalmia neonatorum
30] Long before modern laboratory study, it was epidemiologically observed that nongonococcal urethritis in men was related to cervical infection in women, which in turn was related to ophthalmia neonatorum
in infants born vaginally.
Evidence suggests that the application of topical ocular medications reduces blindness caused by gonococcal ophthalmia neonatorum
and also "protects infants from ocular infection caused by Chlamydia trachomatis1.
Infection during pregnancy may cause spontaneous abortion, stillbirth, prematurity, low birth weight, congenital syphilis, and ophthalmia neonatorum
In addition, because the most common class of infection in the first month of life is primarily caused by STD pathogens present in the birth canal (126), the same mucosal antibodies could be used in a predelivery cervicovaginal lavage or applied to newborns' eyes for studies in the prevention of ophthalmia neonatorum