opsonize

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opsonize

[′äp·sə‚nīz]
(immunology)
To render microorganisms susceptible to phagocytosis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
N-Inf EP, and by the lower CLI observed in group Inf phagocytes stimulated by opsonized zymosan (Table V).
M2b macrophages can be induced by exposure to immune complexes; CD64 agonists opsonized with IgG as erythrocytes are characterized by a phenotype very distinct from M2a and M2c.
As a preliminary experiment, when human whole blood samples were exposed with lower concentrations of NP, significant enhancements of ROS generation were observed in the presence of a low concentration of a typical inflammatory stimulant, opsonized zymosan (Table 5).
Polson et al., "Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies," PLoS One, vol.
Early reports demonstrated that phagocytosis of complement- opsonized zymosan and of complement-opsonized erythrocytes was unaffected by tyrosine kinase inhibitors [97].
But when opsonized zymosan stimulated neutrophils were exposed to high concentrations of the salivary gland extract, superoxide generation and MPO release were significantly reduced.
In general, acute inflammatory response to biomaterials is triggered once these materials are opsonized by host proteins such as IgG and complement cascade.
The engulfment percentage of opsonized and unopsonized SRBCs co- incubation was calculated with some modifications.
SR-A may function to engulf bacteria, viruses, and harmful substances opsonized by CRP in a context of innate immunity.
The same authors reported that MBL opsonized HIV exhibited a 6-fold higher uptake by monocytes.
Inhibition of opsonized zymosan-induced PG[E.sub.2] production occurred at concentrations equivalent to those seen with LPS stimulation.
Phagocytosis of autologous platelets by neutrophilic granulocytes was thought to be an in vitro phenomenon.[3,4] Antiplatelet antibodies have been demonstrated to entice the neutrophilic granulocytes to ingest suitably opsonized platelets.[4] These antibodies are also responsible for the platelet "satellitism" in which the platelets arrange themselves selectively around neutrophils to form rosettes.[5] This patient had platelet "satellitism" when first seen (Figure 1), Her initial electronic platelet count was 65 x [10.sup.9]/L.