The most common HRCT findings in patients with RA-ILD are usual interstitial pneumonia (UIP) (Figure 1), nonspecific interstitial pneumonia (NSIP) (Figure 2), lymphocytic interstitial pneumonia, organizing pneumonia
, diffuse alveolar damage, respiratory bronchiolitis, and desquamative interstitial pneumonia (11).
Report for every sample should include the following: site (segment from which the sample comes), size (2 maximum diameters in perpendicular directions assessed at the microscope), "central sampling" (mainly bronchial with cartilage plates identified or bronchiolar structures in greater than 40% of the surface of the sample), "peripheral sampling" (with or without visceral pleura, with alveoli present in at least 60% of the surface of the sample), and histologic pattern (respiratory bronchiolitis, desquamative interstitial pneumonia, NSIP, organizing pneumonia
, UIP, capillaritis, among others).
Sulfasalazine-induced pulmonary toxicity may manifest in various forms, including subacute interstitial pneumonia, pulmonary infiltration with eosinophilia, desquamative interstitial pneumonia, bronchiolitis obliterans organizing pneumonia
, acute pulmonary edema, eosinophilic pleural effusion, pleural/pericardial hemorrhage or effusion, and antinuclear and anti-histone antibody positivity [I, 3].
Therefore, consolidation may be a sign of CMV pneumonia or organizing pneumonia
accompanied with acute alveolar damage by PCP.
Among all patients, pulmonary sarcoidosis was diagnosed in 12 (24%), malignant disease in 9 (18%), pulmonary tuberculosis (PTB) in 5 (10%), chronic hypersensitivity pneumonitis (CHP) in 4 (8%), organizing pneumonia
(OP) in 3 (6%), slowly resolving bacterial pneumonia in 5 (10%), non-specific interstitial pneumonia (NSIP) in 4 (8%) and others in 3(6%) of patients.
Periengraftment Respiratory Distress syndrome (PERDS), diffuse alveolar hemorrhage (DAH), Idiopathic Pneumonia syndrome (IPS), bronchiolitis obliterans organizing pneumonia
(BOOP), and Bronchiolitis Obliterans syndrome (BOS) are all unique subsets of noninfectious complications (Table 1) (18).
Cryptogenic organizing pneumonia
earlier known as bronchiolitis obliterans organizing pneumonia
(BOOP) is clinically characterized by subacute or chronic respiratory disease for a duration of 2 weeks to 2 months.
Future research will need to evaluate the clinical utility of serum HO-1 measurement in patients with each of the various histopathological diagnoses (e.g., IPF, NSIP, and organizing pneumonia
One case involves bronchiolitis obliterans organizing pneumonia
in a 16-year-old patient not yet diagnosed with SLE.
Idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP), nonspecific interstitial pneumonia (NSIP), and cryptogenic organizing pneumonia
(COP) have gained attention because of their relatively high incidences.
in a young patient being treated with Ustekinumab.
It provides the appropriate sampling particularly in the diagnosis of tuberculosis, organizing pneumonia
(OP), and respiratory bronchiolitis in which the involvement of the disease is apparent in the center of or around the bronchioles and in the diagnosis of some diseases such as lymphangitis carcinomatosa and sarcoidosis which have involvement throughout the lymphatic distribution (2).