organometallic chemistry


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organometallic chemistry,

the reactions and use of a class of compounds (R-M) that contain a covalent bond between carbon and metal. They are prepared either by direct reaction of the metal with an organic compound or by replacement of a metal from another organometallic substance. Their use is based on the polar R-M bond, in which the carbon atom carries a partial negative charge, and on the nature of the metal atom. In synthesis they act as nucleophiles that can bond with relatively positive carbon atoms in compounds such as alkyl halides, aldehydes, and ketones. For example, the Grignard reagent, RMgX (where X equals Br, Cl, or I), and organolithium compounds react with ketones to give secondary alcohols. In industry, butyllithium is used for the polymerization of isoprene in the manufacture of synthetic rubber; metalloorganic compounds serve as catalysts. The semimetals, boron, and silicon are important organometallics; organoboranes are used in synthesis, while organosilicones are polymerized to manufacture plastics and elastomers. Many organometallics are toxic primarily because of the toxicity of the metal. For example tetraethyl leadtetraethyl lead
, (C2H5)4Pb, viscous, colorless, poisonous liquid. It is an organometallic compound prepared by reacting ethyl chloride with a sodium-lead alloy.
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 has been banned as gasoline additive and the conversion of mercury to mercury alkyls by fish has had serious consequences in Japan.
References in periodicals archive ?
Pombeiro presents this extensive research volume commemorating the 2012 International Conference on Organometallic Chemistry (ICOMC).
in Organometallic Chemistry from Loyola University Chicago and conducted post-doctoral research at the University of California, Irvine in protein structural and bio-organic chemistry.
is a partner in the firm's Chemical Patent Prosecution group with expertise in organometallic chemistry, catalysis, polyolefin polymers, polycarbonate plastics, polymer additives, petroleum recovery and refining, and microelectronics manufacturing processes.
Thomas Strassner, Editor, Journal of Organometallic Chemistry, 9:30-11 am
Editor Crabtree (inorganic & organometallic chemistry, Yale U.
Here, we propose the development of novel silicon-based ligands specifically tailored to support organometallic chemistry at first-row transition metals (Fe and Co) and their application to the mechanistic study and development of C-C bond forming reactions.
This reference is intended for scientists and graduate students working in organic and organometallic chemistry, as well as those in bio-, medical, pharmaceutical, and environmental chemistry, and material science.
Since obtaining her PhD in organometallic chemistry from McMaster University in 1990, she has worked in the pharmaceutical industry in several roles over a career of more than 19 years, including progressive roles in Operations and in Regulatory Affairs at Astra Pharma Inc.
This led to the thought -- highly unusual in organometallic chemistry -- of running the reaction in water itself.
com/research/kbpwhf/comprehensive_orga) has announced the addition of Elsevier Science and Technology's new report "Comprehensive Organometallic Chemistry III, 13-Volume Set.
National Academy of Science, his career accomplishments have been further recognized by the Award for Creative Work in Synthetic Organic Chemistry and Award in Organometallic Chemistry of the American Chemical Society (ACS), the Linus Pauling Medal and the MERIT award of the National Institutes of Health.
The prize recognizes research and publication excellence in organic, inorganic, and organometallic chemistry.