organoselenium compound

organoselenium compound

[ȯr¦gan·ə·sə¦lē·nē·əm ′käm‚pau̇nd]
(organic chemistry)
An organic compound that contains both selenium and carbon, and frequently other elements, such as the halogens, oxygen, sulfur, or nitrogen.
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Food and Drug Administration for BXT-51072, an oral, organoselenium compound that exhibits potent anti-inflammatory features, by mimicking glutathione peroxidase (GPx).
The Company's portfolio includes BXT-51072, an organoselenium compound in Phase II clinical trials.
Among the topics are the stem cell paradigm and its application to prostate cancer, interactions between the androgen receptor and other signaling pathways implicated in prostate cancer growth and development, organoselenium compounds as a prospect for therapy, molecular genetic alterations in the prostate cancer microenvironment, implication of lysophosphatidic acid signaling and receptor-mediated mechanisms contributing to the development of prostate carcinoma, redox state and prostate cancer behavior, and how piezoelectric interaction with prostatic crystalloids may explain the relationship between environmental electromagnetic fields and prostate cancer.
In general, organoselenium compounds are more reactive than their sulfur counterparts: the C-Se bond (234 KJ/mol) is weaker than the C-S bond (272 KJ/mol).
AMEX: ALT) has entered into a worldwide exclusive license under which OXIS has granted Alteon exclusive rights to a family of orally bioavailable organoselenium compounds that have demonstrated potent anti-oxidant and anti-inflammatory properties in clinical and preclinical studies.

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