HPV-related nonkeratinizing squamous cell carcinoma of the
oropharynx: utility of microscopic features in predicting patient outcome.
Patients and Tumour Characteristics Characteristics Group I (CBT) Group II (GRT) P-value n (%) n (%) Male 30 (75) 28 (70) 0.61 Female 10 (25) 12 (30) Age 20-40 10 (25) 12 (30) 0.71 40-60 25 (63) 25 (62) 50-30 5 (12) 3 (8) Karnoffsky's Performance status 90-100 19 (47) 21 (53) 0.9 80-90 20 (50) 19 (47) 70-80 1 (3) 0 Primary tumor site Oral Cavity 32 (30) 33 (83) 0.77
Oropharynx 8 (20) 7 (17) Stage III 17 (43) 16 (40) 0.82 IV 23 (57) 24 (60) Nodal stage distribution Characteristics Group I (CBT) Group II (GRT) P-value n (%) n (%) N0 10 (25) 11 (27) 0.90 N1 13 (32) 10 (26) N2 17 (43) 19 (47) N3 0 0 Table 2.
The prevalence of deaths from oral and
oropharynx cancer was 3.75 more in men than in women (Table 3).
All cases of SCC (including two in the
oropharynx) were HPV negative.
In order to confirm these findings, external validation will be performed, and for the case of
oropharynx, tumor HPV infection data will be included.
It is imbedded within the retropharyngeal soft tissues and extends from the level of the
oropharynx through the hypopharynx to the right lateral extrapharyngeal soft tissues (black arrow).
Based on the above, a definitive diagnosis of Stage I (cT1N0M0) squamous cell carcinoma in the right piriform recess of the hypopharynx and primary extramedullary plasmacytoma in the
oropharynx was made.
Venous malformations may arise in any part of the body, although they have a tendency to occur in the head and neck region, including the oral cavity and the
oropharynx (3, 7, 8).
b)
Oropharynx: its upper limit is the nasopharynx lower limit and its lower limit is a perpendicular to the true vertical line Drawn from Point PI (between line 5 and 6 from Fig.
Streptococcus mitis is a member of the viridans group streptococci (VGS) family, which colonizes all surfaces of the
oropharynx [1].
"Even without complete knowledge of biological mechanisms [of how alcohol causes cancer], the epidemiological evidence can support the judgment that alcohol causes cancer of the
oropharynx, larynx, oesophagus, liver, colon, rectum and breast."
Other sites found to be involved were
oropharynx, nasopharynx, maxillary sinus, and salivary gland with lesser frequency [Table 1].