References in periodicals archive ?
A total of 40 participants (40 knees) were included, with 20 osteoarthritic knees in the OA group and 20 healthy knees in the control group.
In osteoarthritic cartilage, however, cells were compressed and elongated more, probably due to altered cartilage integrity.
The present findings also revealed inadequate consumption of vitamins C and E and omega-3 fatty acids, which might worsen the osteoarthritic condition owing to the involvement of these vitamins in collagen synthesis and protein oxidation prevention [19].
All three agents at these maximum daily doses had 100% probability to reach the minimum clinically important difference established in the study when used to reduce osteoarthritic pain.
Downregulation of leptin mRNA translation via small interference RNA molecules inhibits MMP-13 expression in cultured osteoarthritic chondrocytes [45].
In the semiquantitative evaluation of osteoarthritic menisci, the expression of collagen type I marked by immunohistochemical staining of anti-collagen I antibody was significantly lower compared to the macroscopically unaltered menisci.
Patients with osteoarthritic changes who received MSC experienced a significant reduction in pain compared with those who received the control.
Any joint that is injured could become osteoarthritic at a later date.
In addition, the recent study reported that andrographolide suppressed expressions of MMP-1, MMP-3, and MMP-13 in IL-1[beta] stimulated osteoarthritic human chondrocyte culture via NF-kB signal transduction [12].
In a study by Labuda and coworkers, the prevalence of osteoporosis in osteoarthritic patients who underwent total joint arthroplasty was equal to the general age matched population.