Evaluation of osteoclastic
resorption activity using calcium phosphate coating combined with labeled polyanion.
9-11) Coincidental increased activities of osteoblastic and osteoclastic
functions were shown after SCI.
Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic
As described above, the MiT family of transcription factors is involved in melanocytic and osteoclastic
differentiation, and rearrangement of TFE3 or TFEB in t-RCC may result in expression of melanocytic markers, including Melan-A and HMB-45, (18-20) and/or the osteoclastic
protein cathepsin K.
This marker shows changes in osteoclastic
1-4) Sometimes, osteoclastic
activity results in spontaneous regression.
5] The more popular Wargotz and Norris classification differentiates Metaplastic breast cancers into 5 subtypes: spindle-cell, squamous cell, carcinosarcoma, matrix-producing and MpBC with osteoclastic
Nicotine is a direct inhibitor of osteoblast differentiation and also stimulates the osteoclastic
Histological examination of the spicules revealed bone surrounded by occasional osteoclastic
giant cells, and mixed inflammatory cells including neutrophils, macrophages and an occasional eosinophil.
Once injected, they should target sites of vascular calcification in blood vessels, releasing the proteins and inducing osteoclastic
differentiation of the resident macrophages.
The biopsy report of patient also commented upon the replacement of normal bone by proliferating benign looking mononuclear stromal cells and osteoclastic
multinucleated giant cells with hemorrhages.
The primary differential diagnosis of primary giant cell subtype of MFH should be made with rarely seen osteoclastic
giant cell leiomyosarcoma of kidney and osteoclastoma-like undifferentiated carcinoma or undifferentiated carcinoma rich in giant cells.