The non-traumatic causes of AVN include alcoholism, coagulopathies, systemic chemotherapy, chronic liver disease, corticosteroids, decompression sickness, Gaucher disease, gout, haemoglobinopathy, hyperlipidaemia, idiopathic non-traumatic osteonecrosis
, metabolic bone disease, pregnancy, radiation therapy, smoking, systemic lupus erythematosus, DIC, fat embolism syndrome, HIV, deep sea diving, and vasculitis.
Patients with small- or medium-sized Ficat Stage I or II osteonecrosis
on radiographs and ARCO Stage I or II on MRI were included in the study.
Transtrochanteric rotational osteotomy of the femoral head for the treatment of osteonecrosis
Radiographs showed osteonecrosis
and fracture of distal femur around femoral prosthesis which also demonstrated femoral component loosening [Figure 5].
The therapies we assessed for the conservative osteonecrosis
management included bisphosphonates, prostaglandin agents, enoxaparin, statins, hyperbaric oxygen, extracorporeal shockwave therapy, and pulsed electromagnetic field therapy.
Because early diagnosis and immediate treatment of osteonecrosis
is very important, the physician must bear in mind that osteonecrosis
might result from impaired microvascular involvement in even NBD.
Bone Therapeutics (EBR: BOTHE) has completed the recruitment of 44 treated patients for the planned interim analysis of the Phase III trial for PREOB as a treatment of osteonecrosis
, the company disclosed on Thursday.
of the femoral head was first described in 1738 by Munro.
The guidelines also state that, for patients at high risk of fractures, the reduced risk of vertebral fractures associated with bisphosphonate use outweighs the risk of osteonecrosis
or atypical femoral fractures.
Additionally, the report provides an overview of key players involved in therapeutic development for Osteonecrosis
and features dormant and discontinued projects.
Key Words: Osteonecrosis
of the jaw, bone metastases, antibone absorptive therapy, bisphosphonates, denosumab.
MAUI, HAWAII -- Patients with systemic lupus erythematosus (SLE) really need to be placed on bone protection therapy as soon as they start on corticosteroids because their risks of steroid-related osteoporosis and osteonecrosis
are so high, Dr.