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A disease characterized by avascular necrosis of ossification centers followed by regeneration. Also known as Calvé's disease; Kienböck's disease; Köhler's disease; Osgood-Schlatter disease; Scheuermann's disease.



any one of a group of primarily inflammatory diseases of the subcartilaginous portions of long tubular bones and apophyses of short bones of the skeleton that result from specific suppurative infections, for example, tuberculosis, or—less commonly—nonspecific suppurative infections of bones and joints. Osteochondrosis can be provoked by colds and microtraumas caused by physical overexertion. In severe cases, all the bones and joints may be affected. Noninflammatory changes in bones and joints can also be classified as osteochondroses.

The clinical symptoms of osteochondrosis are pain and limited movements in the affected joints. The disease can be detected by roentgenographic examination, but no specific treatment exists. Rest and immobilization in a functionally correct position serve to prevent bone deformities, while the pain can be diminished by heat applications and treatment in a health resort.

References in periodicals archive ?
Genetic Risk Factors for the Development of Osteonecrosis in Children Under Age 10 Treated for Acute Lymphoblastic Leukemia [250]
Humeral head osteonecrosis (ON), surgical site infection, screw penetration, and heterotopic ossification limiting mobility were considered complications.
In making medical decisions relating to the risk of developing MRONJ, as well as the risks and benefits of those medications related to osteonecrosis of the jaw (ONJ);
Glucocorticoid usage is a well-known factor in the development of osteonecrosis of bone.
Soon, Caitlin's doctors realized she had Idiopathic Osteonecrosis, an even more rare condition in which blood supply would not return to the bone.
Delayed post-traumatic osteonecrosis of a vertebral body (Kummell's disease).
The most common serious adverse reactions were osteonecrosis of the jaw and osteomyelitis.
Acute nontraumatic knee pain can be seen in many conditions, such as transient bone marrow edema syndrome, transient regional osteoporosis of the knee, spontaneous osteonecrosis and insufficiency fractures.
Director; Center for Osteonecrosis Research and Education; and Director: Clinical Research Group; Division of Arthritis Surgery; The Johns Hopkins University School of Medicine; Baltimore, Maryland
The combination of features is in keeping with subchondral insufficiency microfracture or previously described spontaneous osteonecrosis of the knee (SONK).
The concern is that after years of use, the drugs may in rare cases actually lead to weaker bones in certain women, contributing to "rare but serious adverse events," including unusual femur fractures, esophageal cancer and osteonecrosis of the jaw, a painful and disfiguring crumbling of the jaw bone.
The FDA put a hold on clinical trials of all three anti-NGF factors in 2010, after cases of osteonecrosis and avascular necrosis--including cases in nonindex joints, "unusual" joints like the shoulder, and in patients with no history of OA were reported in patients treated with tanezumab and in those treated with fulranumab, because of concerns that these irreversible cases might be a class effect.