The parts of
osteosarcoma were quite evident, but without certain morphological signs of telangiectatic type.
Co-corresponding and lead author Rachel Flynn, assistant professor of Pharmacology & Experimental Therapeutics and Medicine at BU, explains, 'This study suggests that inhibiting ATR may be a novel and important strategy in treating cancers that rely on the ALT pathway, including up to 60% of
osteosarcomas and 40% to 60% of glioblastomas.
1) According to literature, cases of primary extraskeletal
osteosarcoma (6) and primary
osteosarcoma in a heterotopic bone (7) have been reported.
Conclusion: Adult
osteosarcoma treated with cisplatin/doxorubicin based chemotherapy and surgery had good outcomes.
The company has developed Canine
Osteosarcoma Vaccine, a novel immunotherapy, using a listeria based antigen delivery system licensed from Advaxis Inc (NASDAQ:ADXS).
5) The histogenesis of primary
osteosarcoma of the breast has not been fully elucidated, though an origin from totipotent mesenchymal cells of the breast stroma or a transformation from a pre-existing fibroadenoma or phyllodes tumor have been suggested.
The enrollment criterion for this study was surgical treatment of an
osteosarcoma in an extremity.
This was a retrospective study of 61 patients treated for
osteosarcoma at the CMJAH tumour unit over the 5-year period January 2007--December 2011.
5:1 male predilection was noted for cases diagnosed as
osteosarcoma.
In the case of
osteosarcoma, it affects teens more than any other age group and the upper arm is one of the most common locations for it to appear, according to the (https://www.
Methods: The SaOS-2 and MG63
osteosarcoma cell lines were opted to experiment and these cells were, respectively, cultured with various concentrations of FA (0 uM, 10 uM, 20 uM, 40 uM) for 72 hours at 37degC.
Although a number of groups have assessed the contribution of clinical parameters--namely, patient age, sex, anatomic site of primary tumor, tumor size, and metastasis at presentation--in predicting survival outcomes for patients with
osteosarcoma, (5-9) there are limited data concerning histopathologic attributes.
