osteosarcoma


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Related to osteosarcoma: chondrosarcoma

osteosarcoma

[¦äs·tē·ō·sär′kō·mə]
(medicine)
A malignant tumor principally composed of anaplastic cells of mesenchymal derivation. Also known as osteogenic sarcoma.
References in periodicals archive ?
Co-corresponding and lead author Rachel Flynn, assistant professor of Pharmacology & Experimental Therapeutics and Medicine at BU, explains, 'This study suggests that inhibiting ATR may be a novel and important strategy in treating cancers that rely on the ALT pathway, including up to 60% of osteosarcomas and 40% to 60% of glioblastomas.
1) According to literature, cases of primary extraskeletal osteosarcoma (6) and primary osteosarcoma in a heterotopic bone (7) have been reported.
Conclusion: Adult osteosarcoma treated with cisplatin/doxorubicin based chemotherapy and surgery had good outcomes.
The company has developed Canine Osteosarcoma Vaccine, a novel immunotherapy, using a listeria based antigen delivery system licensed from Advaxis Inc (NASDAQ:ADXS).
5) The histogenesis of primary osteosarcoma of the breast has not been fully elucidated, though an origin from totipotent mesenchymal cells of the breast stroma or a transformation from a pre-existing fibroadenoma or phyllodes tumor have been suggested.
The enrollment criterion for this study was surgical treatment of an osteosarcoma in an extremity.
This was a retrospective study of 61 patients treated for osteosarcoma at the CMJAH tumour unit over the 5-year period January 2007--December 2011.
5:1 male predilection was noted for cases diagnosed as osteosarcoma.
In the case of osteosarcoma, it affects teens more than any other age group and the upper arm is one of the most common locations for it to appear, according to the (https://www.
Methods: The SaOS-2 and MG63 osteosarcoma cell lines were opted to experiment and these cells were, respectively, cultured with various concentrations of FA (0 uM, 10 uM, 20 uM, 40 uM) for 72 hours at 37degC.
Although a number of groups have assessed the contribution of clinical parameters--namely, patient age, sex, anatomic site of primary tumor, tumor size, and metastasis at presentation--in predicting survival outcomes for patients with osteosarcoma, (5-9) there are limited data concerning histopathologic attributes.