elliptocytosis

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elliptocytosis

[ə‚lip·tə‚sī′tō·səs]
(medicine)
A rare hereditary disease of man characterized by the presence of large numbers of oval or elliptic erythrocytes in the circulating blood.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
SLA4A1 mutations have likewise been associated with abnormal secretion of acid by the kidney (renal tubule acidosis) such as that found in homozygous individuals with Southeast Asian Ovalocytosis (SEO).
Can exchange transfusions using red blood cells from donors with Southeast Asian ovalocytosis prevent or ameliorate cerebral malaria in patients with multi-drug resistant Plasmodium falciparum?
(LDH = lactate dehydrogenase; MCV = mean cell volume; MCHC = mean corpuscular haemoglobin concentration; Hb = haemoglobin; HS = hereditary spherocytosis; HE = hereditary elliptocytosis; HPP = hereditary pyropoikilocytosis; SAO = South East-Asian ovalocytosis; HSt = hereditary stomatocytosis; PCR = polymerase chain reaction; EMA = eosin-5'-maleimide; G6PD = glucose-6-phosphate dehydrogenase.)
A number of specific genomic variants including [beta]-globin locus, G6PD deficiency, Duffy, ovalocytosis, ABO, and human leukocyte antigen confer resistance to malaria in the human host.
In the mother classical cobalamin deficiency features may be produced including macrocytic red blood cells with or without anaemia, ovalocytosis, hyper segmented white blood cells, pancytopenia, atrophic glossitis, stomatitis, malabsorption due to villi atrophy and mucositis (Rush et al., 2014).
This is true of hereditary elliptocytosis, hereditary pyropoikilocytosis and Southeast Asian ovalocytosis, a distinctive type of inherited haemolytic anaemia that is common in some parts of Southeast Asia.