Further studies are necessary to test whether hypothyroidism could modify the amount of cholesterol in the ovarian follicles
depending on their size as has been reported in sheep and cattle [40, 41].
A large number of ovarian follicles
in different stages of development (primordial, primary, preantral, and antral follicles) and corpora lutea with radial strands of luteum cells were separated by a stroma.
Theca: The forgotten cell of the ovarian follicle
. Reproduction 140:489-504.
The rationale of this study was to observe the effects of immobilization stress on the number of ovarian follicles
An osmotic swelling of ovarian follicles
takes place during oocyte maturation.
(1995) Microvasculature in the mouse ovarian follicle
demonstrated by a lectin angiography method.
Altogether, according to above discussion, the first concept coming to mind is that during PCOS condition, constant exposure of oocytes and other ovarian cells to OS, and hormonal alternations predispose the ovarian follicles
to progressive rate of atresia leading to exhausted ovaries with reduced number of intact follicles.
Messenger RNA quantification for inhibin-[beta]A subunit in caprine ovarian follicles
Whereas clomiphene citrate is an orally active, antiestrogenic substance that promotes the release of FSH from the pituitary gland and thus stimulates the development of ovarian follicles
and ovulation (Clark & Markaverich 1981).
In the absence of a dominant ovarian follicle
, no LH surge occurs, and ovulation cannot occur.
Ovulation The process whereby a mature ovarian follicle
ruptures to release the oocyte.