The trial initiation is informed by the positive results of an independent case series which demonstrated that the use of methotrexate with Krystexxa was well tolerated and led to an improved overall response
. In the trial, 135 adult patients will be randomized to receive methotrexate or placebo for four weeks and then receive treatment with Krystexxa and methotrexate or Krystexxa and placebo for 52 weeks, with the primary endpoint measured at Month 6, followed by a six-month follow-up period.
M2 PHARMA-December 12, 2017-Data from Blueprint Medicines Trial of Avapritinib in Patients with Advanced Systemic Mastocytosis Show Excellent Overall Response
and Disease Control Rates
Tenders are invited for this solicitation for professional services is to assist in obtaining weighted behavioral survey data for the high school population by realizing an overall response
rate of 62% or higher, which incorporates both the school response rate and student response rate.
Japan-based Eisai has dosed its first patient in a clinical trial to explore whether or not the company's eribulin in combination with Halozyme Therapeutics' PEGPH20 can improve overall response
rate in women with advanced breast cancer, it was reported yesterday.
In a research note to investors, White says the updated selinexor with Darzalex data "continues to look good," with efficacy results showing an overall response
rate of 73% in Darzalex naive patients versus the EHA abstract data published last month with an ORR of 77%.
The findings showed a significant improvement in overall response
rate for Xilonix-treated patients versus placebo.
"These results are consistent with the overall response
rates observed in earlier studies, validating our research of venetoclax in relapsed/refractory CLL patients including those with the 17p deletion."
The analyst believes Mirati's KRAS G12Ci has potential to exceed AMG510's 50% overall response
rate in non-small cell lung cancer.
Final results of VE-BASKET for the 22 people with ECD showed a best overall response
rate of 54.5 %.
To enhance Kenya Red Cross capacity to prepare and respond to disaster s, through providing a timely and effective response to small and medium disasters; ensuring overall response
effectiveness is improved; maintaining the dignity of people affected by disasters in Kenya by providing direct support to over 3,400 men, women and children per year.
The firm stated that in the trial Opdivo indicated a consistent statistically significant superiority over docetaxel across all secondary endpoints including overall response
rate and progression-free survival.
*The combined factors of experience and capabilities of the firm, cataloging and processing services, electronic capabilities, inventory volume and turnaround time, and the overall response
to the Request for Proposal will be evaluated in awarding the contract(s).