oxygenase


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Related to oxygenase: oxidase, peroxidase, reductase, Heme oxygenase

oxygenase

[′äk·sə·jə‚nās]
(biochemistry)
An oxidoreductase that catalyzes the direct incorporation of oxygen into its substrate.
References in periodicals archive ?
About HBI-002 Hillhurst's lead product, HBI-002, is a proprietary investigational drug product designed to augment the protective cellular heme oxygenase metabolic pathway to limit inflammatory processes, prevent apoptosis (cell death) and prevent oxidative injury.
Transcriptional and post-translational modulation of myo-inositol oxygenase by high glucose and related pathobiological stresses.
The heme oxygenase activity assay followed the modified procedures of Ryter et al.
Preliminary data indicated that heme oxygenase expression was increased in Day 1 Stage I larvae and postmolt juvenile lobsters following exposure to methoprene (data not shown).
Then the cells were lysed on plates, cell lysates were harvested and the quantity of heme oxygenase (HO-1) in cell lysates was measured using Total HO-1 ELISA Kit (R&D Systems) according to the manufacturer's protocol.
35) Researchers at Johns Hopkins showed that resveratrol induces production of the enzyme heme oxygenase, which is protective against oxidative stress.
The scientific importance of the work is that it opened a now blossoming area of research on the beneficial effects of heme catabolism initiated byheme oxygenase (4).
To further understand these properties of nNOS on its active site structural level, we have examined the oxygenase (heme-containing) domain of the two mutants in close comparison with that of wild-type nNOS with UV-visible absorption, magnetic circular dichroism (MCD), and electron paramagnetic resonance (EPR) spectroscopy.
They have further identified lower levels of heme oxygenase I (HO-1), known for its anti-inflammatory and immunosuppressive role, in monocytes from alloimmunized SCD patients and altered monocyte control of Treg development in response to hemin, a surrogate marker for transfused RBC breakdown products.
Stress protein-induced immunosuppression: inhibition of cellular immune effector functions following overexpression of haem oxygenase (HSP 32).
HMOX1 [5] [heme oxygenase (decycling) 1] converts heme to biliverdin, which is reduced by BLVRA (biliverdin reductase A) to bilirubin.

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