pachymeningitis


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pachymeningitis

[¦pak·ē‚men·ən′jīd·əs]
(medicine)
Inflammation of the dura mater.
References in periodicals archive ?
Igg4-related hypertrophic pachymeningitis: Clinical features, diagnostic criteria, and treatment.
IgG4-related disease and hypertrophic pachymeningitis. Medicine (Baltimore) 2013 Jul;92(4):206-216.
Regarding cranial pachymeningitis due to any aetiology, clinical manifestations vary depending on the location of the pathology, and the affected patients commonly present with manifestations of increased intracranial pressure, such as headache, or progressive neurologic deficits arising due to compression of neural structures by the thickened dura mater such as cranial neuropathies including vestibular involvement and seizures [4].
Skodda, "Immunoglobulin-G4- related hypertrophic pachymeningitis with antineutrophil cytoplasmatic antibodies effectively treated with rituximab," Journal of Clinical Neuroscience, vol.
The effects range from simple swelling of the affected organs (salivary and lacrimal glands, lymph nodes) to obstruction (pancreaticobiliary, ureteral), organ dysfunction (pituitary insufficiency secondary to hypophysitis, kidney disease), and even frank medical emergency (aortic dissection, pachymeningitis, pancreatitis).
There are two additional case reports on IgG4-RD involving the sclera: one described an IgG4-RD flare in a patient with a long history of the disease (diagnosis based on extraorbital biopsy, submandibular gland biopsy) [5] and the other was a case of IgG4-related pachymeningitis with concomitant scleritis, uveitis, and orbital soft-tissue involvement [6].
Central nervous system (CNS) involvement is uncommon, occurring in 4-18% of GPA patients [1, 2], and characterized by hypertrophic cranial pachymeningitis (HCP) [3, 4], cranial nerve paralysis [4], cerebral infarction [5-7], and subarachnoid hemorrhage [8, 9].
The differential diagnoses include collision tumour of meningioma and plasmacytoma, inflammatory pseudotumour, idiopathic hypertrophic pachymeningitis (IHP), and intracranial plasma cell granuloma.
(Eg: tuberculomas), tuberculous abscesses, tuberculous cerebritis and pachymeningitis.
Matumoto, "Intracranial hypertrophic pachymeningitis with high perinuclear antineutrophil cytoplasmic antibody (p-ANCA) occurred in a patient on hemodialysis," Clinical Neurology, vol.
MRSA with progression from otitis media and sphenoid sinusitis to clival osteomyelitis, pachymeningitis and abducens nerve palsy in an immunocompetent 10-year-old patient.