papain


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papain:

see papayapapaya
, soft-stemmed tree (Carica papaya) of tropical America resembling a palm with a crown of palmately lobed leaves. It is cultivated for its melonlike yellow fruits eaten raw or cooked and, more recently, for the juice which has become a commercial item.
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Papain

 

a proteolytic vegetable enzyme of the hydrolase class. Papain exhibits a wide range of substrate specificities, catalyzing the hydrolysis of peptide bonds in proteins and peptides and the hydrolysis of amides, ethers, and thioesters. Crystalline papain is obtained from the sap of the papaya tree (Carica papaya), where it is present in large quantities. The papain molecule is made up of a single polypeptide chain that consists of 212 amino-acid residues. Its molecular weight is 20,900, and the amino-acid sequence has been fully worked out. The active site of papain contains a sulfhydryl group (—SH) and a histidine radical. Papain is used to process leather, tenderize meat, and lighten the color of beverages.

REFERENCES

Kretovich, V. L. Osnovy biokhimii rastenii, 5th ed. Moscow, 1971.
Mosolov, V. V. Proteoliticheskie fermenty. Moscow, 1971.

papain

[pə′pī·ən]
(biochemistry)
An enzyme preparation obtained from the juice of the fruit and leaves of the papaya (Carica papaya); contains proteolytic enzymes.
References in periodicals archive ?
Preparation of Cryptides from Natural Actomyosin Using Papain. The NAM pellet of 100 g (3 g of protein) was dispersed in 200 ml of chilled double-distilled water and homogenized at 9000 rpm using the homogenizer for 2 min.
Therefore, we attempted to improve the degree of hydrolysis of DEW by increasing E/S ratio of papain. The peptides content and DH of the hydrolysates of DEW by various E/S ratios were showed in Figure 2.
"These unapproved products have put consumers health in jeopardy, from reports of permanent vision loss with unapproved balanced salt solutions to a serious drop in blood pressure and increased heart rate from the topical papain products," said Janet Woodcock, M.D., director for the CDER.
According to the terms of the renewal, Sullivan Papain Block McGrath & Cannavo, one of New York's largest and most diverse personal injury firms, will continue to occupy the entire 18th floor of 120 Broadway for an additional 10 years.
Local ocular anaphylaxis to papain enzyme contained in a contact lens cleansing solution.
In the same way that papain breaks down undigested protein waste from your food, it can also dissolve the protective biofilm and fibrin that covers parasites, and particularly their eggs, on the walls of your lower intestine.
The canine functional soft chews contain a proprietary blend of organic full spectrum hemp oil, turmeric, papain and bromelain (18 mg).
The magic is in the enzymes papain, a natural digestive enzyme that breaks up foods irritating the stomach and chymopapain, which help break down proteins and soothe the stomach by promoting a healthy acidic environment.
The reductant is comprised of aloe gel or aloe vera, xylitol, ferrous sulfate, sodium bicarbonate, calcium carbonate, zinc gluconate, a salt, bromelain, papain and essential oil.
Enzymes like papain and chymopapain-which are both present in papaya-help in improving healing from burns and inflammation, people with asthma, rheumatoid arthritis and osteoarthritis can benefit from the nutrient of this fruit.
To choose the optimum enzyme to hydrolysate carrot seed protein (CSP), four representative proteases (papain, trypsin, neutrase, and alcalase) were used in the preliminary hydrolysis.