papain


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papain:

see papayapapaya
, soft-stemmed tree (Carica papaya) of tropical America resembling a palm with a crown of palmately lobed leaves. It is cultivated for its melonlike yellow fruits eaten raw or cooked and, more recently, for the juice which has become a commercial item.
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Papain

 

a proteolytic vegetable enzyme of the hydrolase class. Papain exhibits a wide range of substrate specificities, catalyzing the hydrolysis of peptide bonds in proteins and peptides and the hydrolysis of amides, ethers, and thioesters. Crystalline papain is obtained from the sap of the papaya tree (Carica papaya), where it is present in large quantities. The papain molecule is made up of a single polypeptide chain that consists of 212 amino-acid residues. Its molecular weight is 20,900, and the amino-acid sequence has been fully worked out. The active site of papain contains a sulfhydryl group (—SH) and a histidine radical. Papain is used to process leather, tenderize meat, and lighten the color of beverages.

REFERENCES

Kretovich, V. L. Osnovy biokhimii rastenii, 5th ed. Moscow, 1971.
Mosolov, V. V. Proteoliticheskie fermenty. Moscow, 1971.

papain

[pə′pī·ən]
(biochemistry)
An enzyme preparation obtained from the juice of the fruit and leaves of the papaya (Carica papaya); contains proteolytic enzymes.
References in periodicals archive ?
Papain and chymotrypsin hydrolysates were the least.
The protein nature of the molecule was checked by enzymatic treatment with papain and by precipitation with ethanol.
Combines Slippery Elm and Golden Seal to soothe and relieve inflammation; Charcoal to reduce stomach gas and Papain to help digestion.
The tenderizer contained papain, an enzyme that breaks down protein and has long been considered to be an anti-inflammatory effective against the pain-producing proteins in insect venom.
For instance, proteases, such as bromelain and papain act on proteins in the food and assist in digestion, whereas lipases aid in expediting the digestion of lipids present in food items.
As for papain, it comes from unripe papaya; this type breaks down proteins, fats and carbohydrates.
It has been reported that papain promotes proteolytic digestion and thereby increases the protein digestibility of papaya leaf meal [46].
Pancreatic enzymes, Iipases, proteases, trypsin, chemotrypsin, as well as bromelain and papain and Aspergillis sp.
They are Papain (Carica papaya Lynn), Euphorbain (Euphorbia lathyris Willd), Curcain (Jatropa curcas Lynn), Calatropin (Calatropis gigantean Robert brown) and Eravatamin (Ervatomia coronaria Jacq.
omega]]-nitro-L-arginine methyl ester (L-NAME), l,3-dihydro-l-[2-hydro-xy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one (NS1619), lH-[l,2,4]oxadiazolo[4,3-a]-quinoxalin-l-one (ODQ), papain, phorbol 12-myristate 13-acetate (PMA), Rp-cAMP, Rp-cGMP, 9-(terahydro-2-furanyl)-9H-purin-6-amine (SQ 22536) and tetraethylammonium chloride (TEA) were obtained from the Sigma-Aldrich Chemical Co.
Beauty formula contains biotin, MSM (methyl-sulfonylmethane), turmeric, rhubarb, antioxidants, papain and other herbs; Heart Health contains antioxidants, CoQ10, arjuna, ginkgo, garlic and resveratrol; Digest contains seven digestive enzymes along with ginger; Glucozone combines chromium, L-taurine, cinnamon, black plum and lutein; Immuplus contains echinacea, ginseng, natural antioxidants, enzymes and other herbs; Neuro combines bacopa, L-tyrosine, turmeric, ginkgo, ginseng, antioxidants and other ingredients to support brain functioning; Relax contains melatonin, hops, passion flower, valerian and lemon balm; Trim contains L-carnitine, chromium, inositol and other thermogenic herbs and nutrients; and Vision contains lutein, zeaxanthin, betacarotene and antioxidants.
The optimal temperature and pH parameter were listed as follow: papain (40[degrees]C, pH 7.