papaverine


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Related to papaverine: phentolamine, alprostadil, papaverine hydrochloride

papaverine

(pəpăv`ərēn), alkaloid found in opiumopium,
substance derived by collecting and drying the milky juice in the unripe seed pods of the opium poppy, Papaver somniferum. Opium varies in color from yellow to dark brown and has a characteristic odor and a bitter taste.
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 that acts as a muscle relaxant and vasodilator. The drug relaxes the smooth muscle of the larger blood vessels and is used to increase the blood supply to the brain or to the heart, as in the treatment of angina pectorisangina pectoris
, condition characterized by chest pain that occurs when the muscles of the heart receive an insufficient supply of oxygen. This results when the arteries that supply the heart muscle with oxygenated blood are narrowed by arteriosclerosis.
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. It is also used in the treatment of some types of blood clot formation and in the treatment of impotence when the condition is caused by a lack of blood flow.

Papaverine

 

an antispasmodic alkaloid that is found in opium. Papaverine is also produced synthetically. It is used in solutions and tablets for treating such spastic conditions as hypertension, angina pectoris, and irritable colon.

papaverine

[pə′pav·ə‚rēn]
(organic chemistry)
C20H21O4N A white, crystalline alkaloid, melting at 147°C; soluble in acetone and chloroform, insoluble in water; used as a smooth muscle relaxant and weak analgesic, usually as the water-soluble hydrochloride salt.
References in periodicals archive ?
However, the rate of papaverine hydrochloride degradation processes is enhanced as a function of oxygen pressure.
Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
Thebaine is known to be a powerful narcotic which induces sleep and relieves pain while papaverine produces a light sleep since it slows the heart rate.
Papaverine (15-60 mg) and phentolamine (Regitine--mostly used in the combination Trimix preparation--dose of 0.
Summary of reaction metrics and synthesis tree parameters for papaverine synthesis plans Pictet-Gams Decker-Wahl Kernel reaction metrics AE 0.
If the patient does not respond to triple H therapy intracerebral papaverine is another treatment option.
The drugs that failed potency assays were injectable betamethasone, hyaluronidase, papaverine, and progesterone; ophthalmic ciprofloxacin, dexamethasone, and timolol maleate; and oral progesterone.
Drugs such as papaverine hydrochloride, phentolamine, and alprostadil (marketed as Caverject) widen blood vessels.
After unsuccessful attempts to treat the condition with Papaverine and Regitine Dr.
Smoking causes impaired penile flow and interferes with intracavernous papaverine and prostaglandin El effectiveness.
papaverine, phentolamine, prostaglandin) in the early 1980s allowed physicians to study erectile activity and to offer patients an effective alternative to penile implantation.
If, on the other hand, the thought of a painless needle injection doesn't faze you, a satisfactory and much cheaper alternative that your doctor may suggest is papaverine for injection--an old-time smooth-muscle relaxant that has been used successfully in the department of urology at the Indiana University Medical Center.