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A growth pattern of epithelial tumors in which the proliferating epithelial cells grow outward from a surface, accompanied by vascularized cores of connective tissue, to form a branching structure.



a benign tumor of man and animals; its basic structural element is a connective-tissue papilla covered with epithelium and containing vessels. The growth of the papillae in various directions sometimes gives a papilloma the appearance of a cauliflower. The presence of numerous papillomas is called papillomatosis. Papillomas are most commonly found on the skin, although they sometimes occur on mucous membranes. In man, they may be congenital or may result from chronic inflammatory irritation. Some papillomas are viral in origin, for example, those of the sexual organs. The recommended therapy is surgical removal.

Papillomatosis in animals is caused by locally specific viruses. It affects cattle, horses, dogs, and rabbits and occasionally goats, sheep, and wild animals. The infection is caused by diseased animals; natural infection results from contact between diseased and healthy animals. The disease is long in duration. Isolated coral-like papillomas appear and then spread. Their surface is dry, horny, and cracked. When injured, papillomas bleed and become infected and ulcerous. Diagnosis is based on clinical and histological examination. Treatment generally consists of surgical removal.


References in periodicals archive ?
It revealed that a papillary tumor was in the left side of the prostatic urethra with mild inflammatory change on the mucosa (black arrows).
In a description of the pathologic changes of an aggressive papillary tumor of the middle ear in an autopsy temporal bone, widespread deposits of tumor were found at inner ear sites, but no mention was made of involvement of the endolymphatic sac or duct.
This association between iodine excess and papillary tumors has also been suggested in epidemiologic studies in Europe and in the United States (30-33).
Detection of numerical alterations of chromosomes 3, 7, 17, and X in low-grade intracystic papillary tumors of the breast by multi-color fluorescence in situ hybridization.
Intraductal papillary tumors of the major salivary glands: case reports of benign and malignant variants.
The gross ureteral specimen showed multiple papillary tumors in the middle and lower parts of the ureter (Fig.
Biliary papillary tumors share pathological features with intraductal papillary mucinous neoplasm of the pancreas.
Herein we have organized a review describing first oncocytoma and tumors that may be considered in the differential diagnosis, and then high-grade nonpapillary and papillary tumors where a correct diagnosis may need more robust ancillary testing.
To ascertain the presence of invasion in papillary tumors, the presence or absence of myoepithelial cells at the periphery of the tumor has been routinely used by pathologists.
Molecular genetic evidence for the independent origin of multifocal papillary tumors in patients with papillary renal cell carcinomas.
In some cases, serous papillary tumors of the testis and epididymis, particularly those that are borderline tumors of the tunica vaginalis or serous carcinoma of the testis, may be confused with malignant mesothelioma of the tunica vaginalis testis.