Papilloma

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papilloma

[‚pap·ə′lō·mə]
(medicine)
A growth pattern of epithelial tumors in which the proliferating epithelial cells grow outward from a surface, accompanied by vascularized cores of connective tissue, to form a branching structure.

Papilloma

 

a benign tumor of man and animals; its basic structural element is a connective-tissue papilla covered with epithelium and containing vessels. The growth of the papillae in various directions sometimes gives a papilloma the appearance of a cauliflower. The presence of numerous papillomas is called papillomatosis. Papillomas are most commonly found on the skin, although they sometimes occur on mucous membranes. In man, they may be congenital or may result from chronic inflammatory irritation. Some papillomas are viral in origin, for example, those of the sexual organs. The recommended therapy is surgical removal.

Papillomatosis in animals is caused by locally specific viruses. It affects cattle, horses, dogs, and rabbits and occasionally goats, sheep, and wild animals. The infection is caused by diseased animals; natural infection results from contact between diseased and healthy animals. The disease is long in duration. Isolated coral-like papillomas appear and then spread. Their surface is dry, horny, and cracked. When injured, papillomas bleed and become infected and ulcerous. Diagnosis is based on clinical and histological examination. Treatment generally consists of surgical removal.

I. I. VORONIN

References in periodicals archive ?
Secondary CIS: CIS detected during the follow-up of patients with a previous papillary tumor
Natural history of papillary tumor of the pineal region: new insights on biological explanation.
In a description of the pathologic changes of an aggressive papillary tumor of the middle ear in an autopsy temporal bone, widespread deposits of tumor were found at inner ear sites, but no mention was made of involvement of the endolymphatic sac or duct.
Cytogenetic analysis of 6 cell metaphases from the papillary tumor (central) produced a composite karyotype, 49,X[5]+3, +7,+7,+17 (Figure 3), which is consistent with the diagnosis of papillary renal carcinoma.
However, routine cystoscopy frequently overlooks carcinoma in situ and small, solid high-grade or papillary tumors (14,15).
Papillary tumors are localized tumors which can be surgically removed via transurethral resection of the bladder.
To ascertain the presence of invasion in papillary tumors, the presence or absence of myoepithelial cells at the periphery of the tumor has been routinely used by pathologists.
The gross ureteral specimen showed multiple papillary tumors in the middle and lower parts of the ureter (Fig.
CIS with or without papillary tumors or papillary tumors alone) at study entry is disclosed in the conference materials, as is the median DFS interval (in days) of the intent-to-treat population.
Papillomas are discrete benign papillary tumors that develop from the epithelium of the lactiferous ducts.
Based on cytologic features (ie, nuclear to cytoplasmic [N:C] ratio, polarity, and nuclear pleomorphism) obtained from MPM images at high magnification, we were able to grade papillary tumors as either low or high grade, and flat lesions were categorized into benign/reactive or CIS.